Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXD10
  • Mouse genes Hoxd10
  • Rat genes Hoxd10
  • Zfish genes hoxd10a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxd10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Hoxd10	IDA		Mouse	PMID:16672333
Molecular Function	GO:0003677	DNA binding	Hoxd10	IDA		Mouse	PMID:1756725
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Hoxd10	IDA		Mouse	MGI:MGI:5902689|PMID:11432851
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Hoxd10	IDA		Mouse	PMID:1756725
Molecular Function	GO:0005515	protein binding	HOXD10	IPI	UniProtKB:O14893	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXD10	IPI	UniProtKB:O75925	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXD10	IPI	UniProtKB:Q8N594	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXD10	IPI	UniProtKB:Q96D59	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXD10	IPI	UniProtKB:Q9GZS3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXD10	IPI	UniProtKB:Q9NS23-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXD10	IPI	UniProtKB:Q9UNS2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hoxd10	IPI	UniProtKB:P70323	Mouse	MGI:MGI:5559282|PMID:22842189
Molecular Function	GO:0005515	protein binding	Hoxd10	IPI	UniProtKB:O88513	Mouse	MGI:MGI:3038045|PMID:14973489
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Hoxd10	IDA		Mouse	MGI:MGI:5902689|PMID:11432851
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXD10	IDA		Human	PMID:28473536
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	HOXD10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	HOXD10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HOXD10	IDA		Human	GO_REF:0000052
Biological Process	GO:0008344	adult locomotory behavior	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:10642795
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:10642795
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd10	IGI	MGI:MGI:96171	Mouse	PMID:12869760
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxd10	IGI	MGI:MGI:96192	Mouse	PMID:12869760
Biological Process	GO:0030326	embryonic limb morphogenesis	Hoxd10	IGI	MGI:MGI:96192	Mouse	PMID:12869760
Biological Process	GO:0030326	embryonic limb morphogenesis	Hoxd10	IGI	MGI:MGI:96171	Mouse	PMID:12869760
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:10642795
Biological Process	GO:0035136	forelimb morphogenesis	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:10642795
Biological Process	GO:0035137	hindlimb morphogenesis	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:10642795
Biological Process	GO:0050905	neuromuscular process	Hoxd10	IGI	MGI:MGI:96192	Mouse	PMID:18065432
Biological Process	GO:0048935	peripheral nervous system neuron development	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:10642795
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxd10	IDA		Mouse	MGI:MGI:5902689|PMID:11432851
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxd10	IDA		Mouse	PMID:1756725
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hoxd10	IDA		Mouse	PMID:16672333
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxd10	IGI	MGI:MGI:96192	Mouse	PMID:12869760
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxd10	IGI	MGI:MGI:96171	Mouse	PMID:12869760
Biological Process	GO:0010468	regulation of gene expression	Hoxd10	IGI	MGI:MGI:96203	Mouse	PMID:23760953
Biological Process	GO:0010468	regulation of gene expression	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:23760953
Biological Process	GO:0007338	single fertilization	Hoxd10	IGI	MGI:MGI:96203	Mouse	PMID:23760953
Biological Process	GO:0007338	single fertilization	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:23760953
Biological Process	GO:0007519	skeletal muscle tissue development	Hoxd10	IGI	MGI:MGI:96210	Mouse	PMID:10642795
Biological Process	GO:0001501	skeletal system development	Hoxd10	IGI	MGI:MGI:96192	Mouse	PMID:12869760
Biological Process	GO:0001501	skeletal system development	Hoxd10	IMP	MGI:MGI:1934269	Mouse	PMID:9409668
Biological Process	GO:0001501	skeletal system development	Hoxd10	IGI	MGI:MGI:96171	Mouse	PMID:12869760
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	Hoxd10	IGI	MGI:MGI:96192	Mouse	PMID:18065432

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern