Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HDGF
  • Mouse genes Hdgf
  • Rat genes Hdgf
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hdgf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Hdgf	IDA		Rat	PMID:19162039|RGD:8554761
Molecular Function	GO:0005515	protein binding	Hdgf	IPI	PR:Q3UMU9-3	Mouse	PMID:22212508
Molecular Function	GO:0005515	protein binding	Hdgf	IPI	PR:Q3UMU9-1	Mouse	PMID:22212508
Molecular Function	GO:0003723	RNA binding	HDGF	HDA		Human	PMID:22658674
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hdgf	IDA		Rat	PMID:19162039|RGD:8554761
Molecular Function	GO:0003714	transcription corepressor activity	HDGF	IDA		Human	PMID:19162039
Molecular Function	GO:0001222	transcription corepressor binding	HDGF	IPI	UniProtKB:Q13363	Human	PMID:19162039
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDGF	HDA		Human	PMID:27559042
Cellular Component	GO:0005576	extracellular region	HDGF	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	HDGF	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	Hdgf	IDA		Mouse	MGI:MGI:6316717|PMID:21087088
Cellular Component	GO:0005615	extracellular space	Hdgf	IDA		Mouse	PMID:15140875
Cellular Component	GO:0005654	nucleoplasm	HDGF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Hdgf	IDA		Mouse	PMID:15140875
Cellular Component	GO:0005634	nucleus	Hdgf	IDA		Mouse	PMID:14572309
Cellular Component	GO:0005634	nucleus	Hdgf	IDA		Mouse	PMID:22212508
Cellular Component	GO:0005634	nucleus	Hdgf	IDA		Rat	PMID:19162039|RGD:8554761
Cellular Component	GO:0017053	transcription repressor complex	HDGF	IDA		Human	PMID:19162039
Biological Process	GO:0098761	cellular response to interleukin-7	Hdgf	IDA		Mouse	PMID:29581031
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Hdgf	IDA		Mouse	PMID:15140875
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDGF	IDA		Human	PMID:19162039
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hdgf	IDA		Rat	PMID:19162039|RGD:8554761
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hdgf	IDA		Rat	PMID:19162039|RGD:8554761
Biological Process	GO:0034504	protein localization to nucleus	Hdgf	IDA		Rat	PMID:19162039|RGD:8554761

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern