Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNRH1
  • Mouse genes Gnrh1
  • Rat genes Gnrh1
  • Zfish genes gnrh3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnrh1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005183	gonadotropin hormone-releasing hormone activity	Gnrh1	IDA		Rat	PMID:9256511|RGD:9685144
Cellular Component	GO:0043679	axon terminus	Gnrh1	IDA		Rat	PMID:3044520|RGD:9685148
Cellular Component	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane	Gnrh1	IDA		Rat	PMID:2183089|RGD:9685146
Cellular Component	GO:0030425	dendrite	Gnrh1	IDA		Rat	PMID:6183141|RGD:9685145
Cellular Component	GO:0005615	extracellular space	Gnrh1	IDA		Rat	PMID:17283369|RGD:1599843
Cellular Component	GO:0005798	Golgi-associated vesicle	Gnrh1	IDA		Rat	PMID:2183089|RGD:9685146
Cellular Component	GO:0005739	mitochondrion	Gnrh1	IDA		Rat	PMID:2183089|RGD:9685146
Cellular Component	GO:0043005	neuron projection	Gnrh1	IDA		Rat	PMID:11842221|RGD:70537
Cellular Component	GO:1990008	neurosecretory vesicle	Gnrh1	IDA		Rat	PMID:6183141|RGD:9685145
Cellular Component	GO:0043204	perikaryon	Gnrh1	IDA		Rat	PMID:11842221|RGD:70537
Biological Process	GO:0007568	aging	Gnrh1	IEP		Rat	PMID:24914937|RGD:9685044
Biological Process	GO:0007420	brain development	gnrh3	IMP	ZFIN:ZDB-MRPHLNO-061003-1	Zfish	PMID:16934393
Biological Process	GO:0007420	brain development	gnrh3	IMP	ZFIN:ZDB-MRPHLNO-061003-2	Zfish	PMID:16934393
Biological Process	GO:0043010	camera-type eye development	gnrh3	IMP	ZFIN:ZDB-MRPHLNO-061003-1	Zfish	PMID:16934393
Biological Process	GO:0043010	camera-type eye development	gnrh3	IMP	ZFIN:ZDB-MRPHLNO-061003-2	Zfish	PMID:16934393
Biological Process	GO:0044849	estrous cycle	Gnrh1	IEP		Rat	PMID:9075691|RGD:9685070
Biological Process	GO:0007565	female pregnancy	Gnrh1	IEP		Rat	PMID:17283369|RGD:1599843
Biological Process	GO:0030238	male sex determination	Gnrh1	IMP		Rat	PMID:7012206|RGD:9685140
Biological Process	GO:0043066	negative regulation of apoptotic process	Gnrh1	IDA		Rat	PMID:12457038|RGD:728490
Biological Process	GO:0033087	negative regulation of immature T cell proliferation	Gnrh1	IMP		Rat	PMID:11092955|RGD:9685051
Biological Process	GO:2001223	negative regulation of neuron migration	Gnrh1	IDA		Mouse	PMID:23321696
Biological Process	GO:2001223	negative regulation of neuron migration	Gnrh1	IGI	MGI:MGI:1918021	Mouse	PMID:23321696
Biological Process	GO:2001223	negative regulation of neuron migration	Gnrh1	IGI	MGI:MGI:103038	Mouse	PMID:23321696
Biological Process	GO:0042698	ovulation cycle	Gnrh1	IEP		Rat	PMID:16672174|RGD:1599845
Biological Process	GO:0010468	regulation of gene expression	Gnrh1	IMP	MGI:MGI:1856393	Mouse	PMID:17332066
Biological Process	GO:2000354	regulation of ovarian follicle development	Gnrh1	IMP	MGI:MGI:1856393	Mouse	PMID:10803590
Biological Process	GO:0031960	response to corticosteroid	Gnrh1	IEP		Rat	PMID:16839661|RGD:1599844
Biological Process	GO:0045471	response to ethanol	Gnrh1	IDA		Mouse	PMID:7771642
Biological Process	GO:0032496	response to lipopolysaccharide	Gnrh1	IEP		Rat	PMID:9075691|RGD:9685070
Biological Process	GO:0014070	response to organic cyclic compound	Gnrh1	IEP		Rat	PMID:3282935|RGD:9685069
Biological Process	GO:0043434	response to peptide hormone	Gnrh1	IEP		Rat	PMID:7760850|RGD:9685050
Biological Process	GO:0035864	response to potassium ion	Gnrh1	IEP		Rat	PMID:3282935|RGD:9685069
Biological Process	GO:1990637	response to prolactin	Gnrh1	IEP		Rat	PMID:7760850|RGD:9685050
Biological Process	GO:0034695	response to prostaglandin E	Gnrh1	IEP		Rat	PMID:3282935|RGD:9685069
Biological Process	GO:0048545	response to steroid hormone	Gnrh1	IMP	MGI:MGI:1856393	Mouse	PMID:17332066
Biological Process	GO:0033574	response to testosterone	Gnrh1	IEP		Rat	PMID:9771467|RGD:9685049
Biological Process	GO:0007548	sex differentiation	gnrh3	IMP	ZFIN:ZDB-GENO-201021-5	Zfish	PMID:31758175

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern