|Human Homolog||GNRH1, gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)|
|NCBI Gene ID||2796|
|Human Synonyms||GNRH, GRH, HH12, LHRH, LNRH|
|Human Chr (Location)||8p21-p11.2; chr8:25419258-25425040 (-) GRCh38|
|Disease Associations||(2) Diseases Associated with Human GNRH1|
Homozygous mutants are characterized by the failure of the sex organs to develop postnatally, resulting in sterility in both males and females. Deficiency in hypothalamic GnRH results in deficiencies of LH, FSH and gonadal steroids.
|Process||male sex determination, multicellular organismal development, ...|
|Component||axon terminus, cytoplasmic side of rough endoplasmic reticulum membrane, ...|
|Function||gonadotropin hormone-releasing hormone activity, hormone activity|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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