Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNB3
  • Mouse genes Gnb3
  • Rat genes Gnb3
  • Zfish genes gnb3a,gnb3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051020	GTPase binding	GNB3	IPI	UniProtKB:Q96D21	Human	PMID:19255495
Molecular Function	GO:0005515	protein binding	GNB3	IPI	UniProtKB:P32302	Human	PMID:23773523
Molecular Function	GO:0030507	spectrin binding	Gnb3	IDA		Rat	PMID:23704327|RGD:8553853
Cellular Component	GO:0044297	cell body	Gnb3	IDA		Rat	PMID:9648884|RGD:6893645
Cellular Component	GO:0030425	dendrite	Gnb3	IDA		Mouse	PMID:12454992
Cellular Component	GO:0070062	extracellular exosome	GNB3	HDA		Human	PMID:23533145
Cellular Component	GO:0005834	heterotrimeric G-protein complex	Gnb3	IPI	PR:Q9JMF3	Mouse	PMID:10570481
Cellular Component	GO:0043005	neuron projection	Gnb3	IDA		Rat	PMID:9648884|RGD:6893645
Biological Process	GO:0006884	cell volume homeostasis	GNB3	IGI	UniProtKB:Q61011	Human	PMID:29206867
Biological Process	GO:0090181	regulation of cholesterol metabolic process	GNB3	IGI	UniProtKB:Q61011	Human	PMID:29206867
Biological Process	GO:0045598	regulation of fat cell differentiation	GNB3	IGI	UniProtKB:Q61011	Human	PMID:29206867
Biological Process	GO:0010468	regulation of gene expression	GNB3	IGI	UniProtKB:Q61011	Human	PMID:29206867
Biological Process	GO:0010906	regulation of glucose metabolic process	GNB3	IGI	UniProtKB:Q61011	Human	PMID:29206867
Biological Process	GO:0032350	regulation of hormone metabolic process	GNB3	IGI	UniProtKB:Q61011	Human	PMID:29206867
Biological Process	GO:1903725	regulation of phospholipid metabolic process	GNB3	IGI	UniProtKB:Q61011	Human	PMID:29206867
Biological Process	GO:0090207	regulation of triglyceride metabolic process	GNB3	IGI	UniProtKB:Q61011	Human	PMID:29206867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern