| GO term: | spectrin binding |
| GO id: | GO:0030507 |
| Definition: | Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionbindingprotein bindingcytoskeletal protein bindingactin binding +actinin binding +ankyrin bindingcytoskeletal adaptor activitycytoskeletal regulatory protein bindingdynactin bindingFATZ bindingfilamin bindingkinesin binding +myosin binding +spectrin binding [GO:0030507] (12 genes, 13 annotations)tau protein bindingtelethonin bindingtitin bindingtropomyosin bindingtroponin C bindingtroponin I bindingtroponin T bindingtubulin binding +vinculin bindingMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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