Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GJC1
  • Mouse genes Gjc1
  • Rat genes Gjc1
  • Zfish genes gjc1,gjc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gjc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005243	gap junction channel activity	Gjc1	IDA		Rat	PMID:11668048|RGD:628534
Molecular Function	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	Gjc1	IMP		Mouse	MGI:MGI:5544102|PMID:22982984
Molecular Function	GO:0005216	monoatomic ion channel activity	Gjc1	IGI	MGI:MGI:2384150	Mouse	PMID:15879306
Molecular Function	GO:0005515	protein binding	GJC1	IPI	UniProtKB:O95236-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJC1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJC1	IPI	UniProtKB:Q6ZP29-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJC1	IPI	UniProtKB:Q8N2M4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gjc1	IPI	UniProtKB:P97792	Mouse	MGI:MGI:3814765|PMID:18636119
Molecular Function	GO:0005515	protein binding	Gjc1	IPI	UniProtKB:P23242	Mouse	MGI:MGI:3808971|PMID:18055446
Cellular Component	GO:0005922	connexin complex	Gjc1	IGI	MGI:MGI:2384150	Mouse	PMID:15879306
Cellular Component	GO:0005921	gap junction	Gjc1	IDA		Mouse	PMID:11922902
Cellular Component	GO:0005921	gap junction	Gjc1	IDA		Rat	PMID:11668048|RGD:628534
Biological Process	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling	Gjc1	IMP		Mouse	MGI:MGI:5544102|PMID:22982984
Biological Process	GO:0048738	cardiac muscle tissue development	Gjc1	IMP	MGI:MGI:2177600,MGI:MGI:3608701	Mouse	PMID:14681043
Biological Process	GO:0048468	cell development	Gjc1	IMP	MGI:MGI:2177600,MGI:MGI:3608701	Mouse	PMID:14681043
Biological Process	GO:0007267	cell-cell signaling	Gjc1	IMP	MGI:MGI:2386124	Mouse	PMID:15659592
Biological Process	GO:0007267	cell-cell signaling	Gjc1	IDA		Rat	PMID:11668048|RGD:628534
Biological Process	GO:0007268	chemical synaptic transmission	Gjc1	IMP	MGI:MGI:2386124	Mouse	PMID:15659592
Biological Process	GO:0016264	gap junction assembly	Gjc1	IMP		Mouse	MGI:MGI:5544102|PMID:22982984
Biological Process	GO:0007507	heart development	Gjc1	IMP	MGI:MGI:2177600,MGI:MGI:3608701	Mouse	PMID:14681043
Biological Process	GO:0001570	vasculogenesis	Gjc1	IMP	MGI:MGI:2386124	Mouse	PMID:10976050
Biological Process	GO:0007601	visual perception	Gjc1	IMP	MGI:MGI:2386124	Mouse	PMID:15659592

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern