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Gene Ontology Browser
Term Detail
GO term:gap junction channel activity
Synonym: connexin
Synonym: innexin
Synonym: innexin channel activity
Synonym: intercellular channel
GO id:GO:0005243
Definition:A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-awide pore channel activity
                                                        is-agap junction channel activity [GO:0005243] (13 genes, 18 annotations)
                                                                is-agap junction channel activity involved in cardiac conduction electrical coupling +
                                                                part-ofgap junction hemi-channel activity
                                                        is-agap junction hemi-channel activity
                                                        is-aporin activity +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory