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Gene Ontology Browser
Term Detail
GO term:cell-cell signaling
Synonym: cell-cell signalling
GO id:GO:0007267
Definition:Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-aaxon target recognition
                                        is-acell communication by chemical coupling +
                                        is-acell communication by electrical coupling +
                                        is-acell communication involved in cardiac conduction +
                                        is-acell-cell signaling [GO:0007267] (1271 genes, 2726 annotations)
                                                is-aastrocyte-dopaminergic neuron signaling
                                                is-aautocrine signaling
                                                part-ofcell surface receptor signaling pathway involved in cell-cell signaling +
                                                is-acell-cell signaling by wnt +
                                                is-acell-cell signaling involved in amphid sensory organ development
                                                is-acell-cell signaling involved in cardiac conduction +
                                                is-acell-cell signaling involved in cell fate commitment +
                                                is-acell-cell signaling involved in cell-cell junction organization
                                                is-acell-cell signaling involved in kidney development +
                                                is-acell-cell signaling involved in lung development +
                                                is-acell-cell signaling involved in mammary gland development
                                                is-acell-cell signaling involved in placenta development
                                                is-acell-cell signaling involved in quorum sensing
                                                is-acerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +
                                                is-adetermination of muscle attachment site
                                                is-aectoderm and mesoderm interaction
                                                is-aendocrine signaling
                                                is-aendodermal-mesodermal cell signaling +
                                                is-aepiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
                                                is-aepithelial-mesenchymal cell signaling +
                                                is-amesenchymal-epithelial cell signaling +
                                                is-amesodermal-endodermal cell signaling +
                                                is-aparacrine signaling
                                                is-aregulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
                                                is-aregulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
                                                is-aregulation of pre-tubular aggregate formation by cell-cell signaling
                                                part-ofsignal release +
                                                is-astromal-epithelial cell signaling involved in prostate gland development
                                                is-asynaptic signaling +
                                                is-avisceral mesoderm-endoderm interaction involved in midgut development
                                        is-acellular response to extracellular stimulus +
                                        is-aextracellular matrix-cell signaling +
                                        is-amotogenic signaling initiating cell movement in cerebral cortex +
                                        is-amotogenic signaling involved in interneuron migration from the subpallium to the cortex
                                        is-amotogenic signaling involved in postnatal olfactory bulb interneuron migration
                                        negatively-regulatesnegative regulation of cell communication +
                                        is-apollen-pistil interaction +
                                        positively-regulatespositive regulation of cell communication +
                                        is-aregulation of basal lamina disassembly involved in semicircular canal fusion by cell communication
                                        regulatesregulation of cell communication +
                                        is-aresponse to pheromone involved in conjugation with mutual genetic exchange +
                                        is-asex determination, somatic-gonadal interaction
                                        part-ofsignal transduction +
                                        part-oftransmission of nerve impulse +


obsolete Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling [GO:0007267] (1271 genes, 2726 annotations)
                                        is-aastrocyte-dopaminergic neuron signaling
                                        is-aautocrine signaling
                                        part-ofcell surface receptor signaling pathway involved in cell-cell signaling +
                                        is-acell-cell signaling by wnt +
                                        is-acell-cell signaling involved in amphid sensory organ development
                                        is-acell-cell signaling involved in cardiac conduction +
                                        is-acell-cell signaling involved in cell fate commitment +
                                        is-acell-cell signaling involved in cell-cell junction organization
                                        is-acell-cell signaling involved in kidney development +
                                        is-acell-cell signaling involved in lung development +
                                        is-acell-cell signaling involved in mammary gland development
                                        is-acell-cell signaling involved in placenta development
                                        is-acell-cell signaling involved in quorum sensing
                                        is-acerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +
                                        is-adetermination of muscle attachment site
                                        is-aectoderm and mesoderm interaction
                                        is-aendocrine signaling
                                        is-aendodermal-mesodermal cell signaling +
                                        is-aepiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
                                        is-aepithelial-mesenchymal cell signaling +
                                        is-amesenchymal-epithelial cell signaling +
                                        is-amesodermal-endodermal cell signaling +
                                        is-aparacrine signaling
                                        is-aregulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
                                        is-aregulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
                                        is-aregulation of pre-tubular aggregate formation by cell-cell signaling
                                        part-ofsignal release +
                                        is-astromal-epithelial cell signaling involved in prostate gland development
                                        is-asynaptic signaling +
                                        is-avisceral mesoderm-endoderm interaction involved in midgut development
                                is-aextracellular matrix-cell signaling +
                                is-amotogenic signaling initiating cell movement in cerebral cortex +
                                is-amotogenic signaling involved in interneuron migration from the subpallium to the cortex
                                is-amotogenic signaling involved in postnatal olfactory bulb interneuron migration
                                is-amulticellular organismal signaling +
                                negatively-regulatesnegative regulation of signaling +
                                positively-regulatespositive regulation of signaling +
                                part-ofsignal transduction +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling [GO:0007267] (1271 genes, 2726 annotations)
                                        is-aastrocyte-dopaminergic neuron signaling
                                        is-aautocrine signaling
                                        part-ofcell surface receptor signaling pathway involved in cell-cell signaling +
                                        is-acell-cell signaling by wnt +
                                        is-acell-cell signaling involved in amphid sensory organ development
                                        is-acell-cell signaling involved in cardiac conduction +
                                        is-acell-cell signaling involved in cell fate commitment +
                                        is-acell-cell signaling involved in cell-cell junction organization
                                        is-acell-cell signaling involved in kidney development +
                                        is-acell-cell signaling involved in lung development +
                                        is-acell-cell signaling involved in mammary gland development
                                        is-acell-cell signaling involved in placenta development
                                        is-acell-cell signaling involved in quorum sensing
                                        is-acerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +
                                        is-adetermination of muscle attachment site
                                        is-aectoderm and mesoderm interaction
                                        is-aendocrine signaling
                                        is-aendodermal-mesodermal cell signaling +
                                        is-aepiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
                                        is-aepithelial-mesenchymal cell signaling +
                                        is-amesenchymal-epithelial cell signaling +
                                        is-amesodermal-endodermal cell signaling +
                                        is-aparacrine signaling
                                        is-aregulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
                                        is-aregulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
                                        is-aregulation of pre-tubular aggregate formation by cell-cell signaling
                                        part-ofsignal release +
                                        is-astromal-epithelial cell signaling involved in prostate gland development
                                        is-asynaptic signaling +
                                        is-avisceral mesoderm-endoderm interaction involved in midgut development
                                is-aextracellular matrix-cell signaling +
                                is-amotogenic signaling initiating cell movement in cerebral cortex +
                                is-amotogenic signaling involved in interneuron migration from the subpallium to the cortex
                                is-amotogenic signaling involved in postnatal olfactory bulb interneuron migration
                                is-amulticellular organismal signaling +
                                negatively-regulatesnegative regulation of signaling +
                                positively-regulatespositive regulation of signaling +
                                part-ofsignal transduction +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-aaxon target recognition
                                        is-acell communication by chemical coupling +
                                        is-acell communication by electrical coupling +
                                        is-acell communication involved in cardiac conduction +
                                        is-acell-cell signaling [GO:0007267] (1271 genes, 2726 annotations)
                                                is-aastrocyte-dopaminergic neuron signaling
                                                is-aautocrine signaling
                                                part-ofcell surface receptor signaling pathway involved in cell-cell signaling +
                                                is-acell-cell signaling by wnt +
                                                is-acell-cell signaling involved in amphid sensory organ development
                                                is-acell-cell signaling involved in cardiac conduction +
                                                is-acell-cell signaling involved in cell fate commitment +
                                                is-acell-cell signaling involved in cell-cell junction organization
                                                is-acell-cell signaling involved in kidney development +
                                                is-acell-cell signaling involved in lung development +
                                                is-acell-cell signaling involved in mammary gland development
                                                is-acell-cell signaling involved in placenta development
                                                is-acell-cell signaling involved in quorum sensing
                                                is-acerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +
                                                is-adetermination of muscle attachment site
                                                is-aectoderm and mesoderm interaction
                                                is-aendocrine signaling
                                                is-aendodermal-mesodermal cell signaling +
                                                is-aepiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
                                                is-aepithelial-mesenchymal cell signaling +
                                                is-amesenchymal-epithelial cell signaling +
                                                is-amesodermal-endodermal cell signaling +
                                                is-aparacrine signaling
                                                is-aregulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
                                                is-aregulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
                                                is-aregulation of pre-tubular aggregate formation by cell-cell signaling
                                                part-ofsignal release +
                                                is-astromal-epithelial cell signaling involved in prostate gland development
                                                is-asynaptic signaling +
                                                is-avisceral mesoderm-endoderm interaction involved in midgut development
                                        is-acellular response to extracellular stimulus +
                                        is-aextracellular matrix-cell signaling +
                                        is-amotogenic signaling initiating cell movement in cerebral cortex +
                                        is-amotogenic signaling involved in interneuron migration from the subpallium to the cortex
                                        is-amotogenic signaling involved in postnatal olfactory bulb interneuron migration
                                        negatively-regulatesnegative regulation of cell communication +
                                        is-apollen-pistil interaction +
                                        positively-regulatespositive regulation of cell communication +
                                        is-aregulation of basal lamina disassembly involved in semicircular canal fusion by cell communication
                                        regulatesregulation of cell communication +
                                        is-aresponse to pheromone involved in conjugation with mutual genetic exchange +
                                        is-asex determination, somatic-gonadal interaction
                                        part-ofsignal transduction +
                                        part-oftransmission of nerve impulse +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory