Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GFER
  • Mouse genes Gfer
  • Rat genes Gfer
  • Zfish genes gfer
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gfer

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	GFER	IDA		Human	PMID:22224850
Molecular Function	GO:0016971	flavin-linked sulfhydryl oxidase activity	Gfer	IDA		Rat	PMID:11346147|RGD:9685721
Molecular Function	GO:0016971	flavin-linked sulfhydryl oxidase activity	gfer	IMP		Zfish	PMID:22292055
Molecular Function	GO:0016971	flavin-linked sulfhydryl oxidase activity	gfer	IDA		Zfish	PMID:22292055
Molecular Function	GO:0042802	identical protein binding	gfer	IPI	ZFIN:ZDB-GENE-060810-186	Zfish	PMID:22292055
Molecular Function	GO:0005515	protein binding	GFER	IPI	UniProtKB:Q7Z465	Human	PMID:12681488
Molecular Function	GO:0005515	protein binding	GFER	IPI	UniProtKB:Q8N4Q1	Human	PMID:23676665
Molecular Function	GO:0005515	protein binding	GFER	IPI	UniProtKB:Q9H8W4	Human	PMID:25416956
Molecular Function	GO:0015035	protein-disulfide reductase activity	GFER	IDA		Human	PMID:22224850
Cellular Component	GO:0005737	cytoplasm	gfer	IDA		Zfish	PMID:22292055
Cellular Component	GO:0005829	cytosol	GFER	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Gfer	IDA		Rat	PMID:18272248|RGD:9685729
Cellular Component	GO:0005615	extracellular space	Gfer	IDA		Rat	PMID:10216127|RGD:9685731
Cellular Component	GO:0005739	mitochondrion	GFER	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	GFER	IDA		Human	PMID:23676665
Cellular Component	GO:0005739	mitochondrion	Gfer	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Gfer	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Gfer	IDA		Rat	PMID:18272248|RGD:9685729
Cellular Component	GO:0005739	mitochondrion	gfer	IDA		Zfish	PMID:22292055
Biological Process	GO:0072717	cellular response to actinomycin D	Gfer	IEP		Rat	PMID:23073658|RGD:9685733
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Gfer	IEP		Rat	PMID:23073658|RGD:9685733
Biological Process	GO:0097237	cellular response to toxic substance	Gfer	IEP		Rat	PMID:23073658|RGD:9685733
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Gfer	IEP		Rat	PMID:23073658|RGD:9685733
Biological Process	GO:0007507	heart development	gfer	IMP	ZFIN:ZDB-MRPHLNO-130516-7	Zfish	PMID:23597483
Biological Process	GO:0001889	liver development	gfer	IMP	ZFIN:ZDB-MRPHLNO-120208-2	Zfish	PMID:22292055
Biological Process	GO:0097421	liver regeneration	Gfer	IMP		Rat	PMID:24880092|RGD:9685725
Biological Process	GO:0043066	negative regulation of apoptotic process	Gfer	IMP		Rat	PMID:18272248|RGD:9685729
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	Gfer	IDA		Rat	PMID:9021955|RGD:9685777
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	Gfer	IDA		Rat	PMID:16937468|RGD:9685728
Biological Process	GO:0032496	response to lipopolysaccharide	Gfer	IEP		Rat	PMID:23073658|RGD:9685733

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern