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Gfer
Gene Detail
 Symbol
Name
ID
Gfer
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
MGI:107757
Synonyms Alr, ERV1
Feature Type protein coding gene
Genetic Map
Chromosome 17
12.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:24693191-24696156 bp, - strand
From NCBI annotation of GRCm38

  2966 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55884  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: mitochondrial sulfhydryl oxidase Erv1p/ALR
Gene Tree: Gfer

Human
homologs
Human Homolog GFER, growth factor, augmenter of liver regeneration
NCBI Gene ID 2671
neXtProt AC  NX_P55789
Human Synonyms  ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS
Human Chr (Location)  16p13.3-p13.12; chr16:1984149-1987749 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human GFER
Alleles
and
phenotypes
All alleles(15) : Gene trapped(13) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process oxidation-reduction process
Component cytoplasm, mitochondrion
Function flavin adenine dinucleotide binding, growth factor activity, ...
External Resources: FuncBase
Expression
cDNA source data(70)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(74) Genomic(3) cDNA(70) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000040888 (Evidence)
Entrez Gene11692 (Evidence)
UniGene28124
DFCITC1579158, TC1587206
DoTSDT.101169685, DT.101409956, DT.94333531
NIA Mouse Gene IndexU037533
EC1.8.3.2
Consensus CDS ProjectCCDS28492.1
International Mouse Knockout Project StatusGfer
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 11692 NCBI Gene Model | MGI Sequence Detail 2966 C57BL/6J ±  kb
transcript NM_023040 RefSeq | MGI Sequence Detail 1775 C57BL/6 
polypeptide P56213 UniProt | EBI | MGI Sequence Detail 198 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(7) UniProt(1)
Polymorphisms RFLP(1) : SNPs within 2kb(42 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017905 ERV/ALR sulphydryl oxidase
Protein Ontology PR:000007940 FAD-linked sulfhydryl oxidase ALR
Graphical View of Protein Domain Structure
References (Earliest) J:35860 Giorda R, et al., Analysis of the structure and expression of the augmenter of liver regeneration (ALR) gene. Mol Med. 1996 Jan;2(1):97-108
(Latest) J:182992 Teng EC, et al., Gfer inhibits Jab1-mediated degradation of p27kip1 to restrict proliferation of hematopoietic stem cells. Mol Biol Cell. 2011 Apr 15;22(8):1312-20
All references(35)
Other
accession IDs
MGD-MRK-36333

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory