Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gapdh

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GAPDH
- Mouse genes Gapdh
- Rat genes Gapdh
- Zfish genes gapdh
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gapdh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019828	aspartic-type endopeptidase inhibitor activity	GAPDH	IDA		Human	PMID:22832495
Molecular Function	GO:0097718	disordered domain specific binding	GAPDH	IPI	UniProtKB:P21758	Human	PMID:11785981
Molecular Function	GO:0019899	enzyme binding	Gapdh	IPI	UniProtKB:Q8VCN5	Mouse	MGI:MGI:5315686\|PMID:19903941
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Gapdh	IDA		Mouse	MGI:MGI:5315686\|PMID:19903941
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Gapdh	IDA		Mouse	PMID:176725
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Gapdh	IDA		Mouse	PMID:28258188
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Gapdh	IMP		Mouse	PMID:15665293
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Gapdh	IMP	MGI:MGI:2183515	Mouse	PMID:3796661
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Gapdh	IDA		Rat	PMID:15720133\|RGD:2302795
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Gapdh	IDA		Rat	PMID:15951807\|RGD:8554488
Molecular Function	GO:0042802	identical protein binding	GAPDH	IPI	UniProtKB:P04406	Human	PMID:20392205
Molecular Function	GO:0042802	identical protein binding	GAPDH	IPI	UniProtKB:P04406	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	Gapdh	IPI	RGD:2661	Rat	PMID:27129213\|RGD:11574725
Molecular Function	GO:0008017	microtubule binding	Gapdh	IDA		Rat	PMID:15312048\|RGD:8553423
Molecular Function	GO:0035605	peptidyl-cysteine S-nitrosylase activity	Gapdh	IDA		Rat	PMID:20972425\|RGD:8554381
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P41743	Human	PMID:11724794
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P23381	Human	PMID:15628863
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P15927	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00533	Human	PMID:16799092
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:O95292	Human	PMID:17540579
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00533	Human	PMID:20029029
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00558	Human	PMID:20392205
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P12004	Human	PMID:20849852
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q12933	Human	PMID:23332158
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P48147	Human	PMID:23348613
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P21754	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q05996	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q12836	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P05109	Human	PMID:25417112
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P35228	Human	PMID:25417112
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q13114	Human	PMID:27387501
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P42695	Human	PMID:29028794
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00441	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:O00471	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:O75344	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P06241	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P10599	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P17612	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P35222	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q14194	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q6UY14-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q8NEA9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q8WUY3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q92993-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q96GZ6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9BPW9-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9UHX1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9UIJ7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9UQM7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:Q08460	Mouse	MGI:MGI:3852248\|PMID:19423573
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:P23819	Mouse	MGI:MGI:6224103\|PMID:27461448
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:P61023	Rat	PMID:15312048\|RGD:8553423
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:Q80Z30	Rat	PMID:15680915\|RGD:8553307
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:Q920M9	Rat	PMID:15951807\|RGD:8554488
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:P19357	Rat	PMID:16396496\|RGD:8553682
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	RGD:1304683	Rat	PMID:18028335\|RGD:2302128
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:D3ZUQ0	Rat	PMID:19607794\|RGD:8553565
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:Q920M9	Rat	PMID:19607794\|RGD:8553565
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:P47196	Rat	PMID:20488185\|RGD:8554327
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:P70288	Rat	PMID:20972425\|RGD:8554381
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:P97313	Rat	PMID:20972425\|RGD:8554381
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	UniProtKB:Q923E4	Rat	PMID:20972425\|RGD:8554381
Molecular Function	GO:0005515	protein binding	Gapdh	IPI	RGD:3710	Rat	PMID:20980406\|RGD:10450535
Cellular Component	GO:0005737	cytoplasm	GAPDH	IDA		Human	PMID:11785981
Cellular Component	GO:0005737	cytoplasm	GAPDH	IDA		Human	PMID:24507776
Cellular Component	GO:0005737	cytoplasm	Gapdh	IDA		Mouse	MGI:MGI:4353867\|PMID:19470756
Cellular Component	GO:0005737	cytoplasm	Gapdh	IDA		Mouse	PMID:21539824
Cellular Component	GO:0005737	cytoplasm	Gapdh	IDA		Mouse	PMID:17962088
Cellular Component	GO:0005737	cytoplasm	Gapdh	IDA		Mouse	PMID:15159393
Cellular Component	GO:0005737	cytoplasm	Gapdh	IDA		Mouse	PMID:18698006
Cellular Component	GO:0005737	cytoplasm	Gapdh	IDA		Mouse	PMID:19075228
Cellular Component	GO:0005737	cytoplasm	Gapdh	IDA		Rat	PMID:15312048\|RGD:8553423
Cellular Component	GO:0005829	cytosol	GAPDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	GAPDH	IDA		Human	PMID:24101517
Cellular Component	GO:0005829	cytosol	GAPDH	IDA		Human	PMID:28404743
Cellular Component	GO:0005829	cytosol	Gapdh	IDA		Mouse	PMID:24137001
Cellular Component	GO:0005829	cytosol	Gapdh	IDA		Mouse	PMID:21347706
Cellular Component	GO:0005829	cytosol	Gapdh	IDA		Mouse	PMID:21413931
Cellular Component	GO:0005829	cytosol	Gapdh	IDA		Mouse	PMID:23530063
Cellular Component	GO:0005829	cytosol	Gapdh	IDA		Rat	PMID:15951807\|RGD:8554488
Cellular Component	GO:0005829	cytosol	Gapdh	IDA		Rat	PMID:1834654\|RGD:1599371
Cellular Component	GO:0005829	cytosol	Gapdh	IDA		Rat	PMID:19607794\|RGD:8553565
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:12519789
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:23533145
Cellular Component	GO:0097452	GAIT complex	GAPDH	IDA		Human	PMID:15479637
Cellular Component	GO:0097452	GAIT complex	GAPDH	IDA		Human	PMID:23071094
Cellular Component	GO:0097452	GAIT complex	Gapdh	IDA		Mouse	PMID:23071094
Cellular Component	GO:0098978	glutamatergic synapse	Gapdh	IDA		Rat	PMID:9371836\|RGD:13702148
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GAPDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005811	lipid droplet	GAPDH	IDA		Human	PMID:14741744
Cellular Component	GO:0016020	membrane	GAPDH	HDA		Human	PMID:19946888
Cellular Component	GO:0015630	microtubule cytoskeleton	Gapdh	IDA		Rat	PMID:15312048\|RGD:8553423
Cellular Component	GO:0005739	mitochondrion	Gapdh	HDA		Mouse	PMID:14651853
Cellular Component	GO:0043209	myelin sheath	Gapdh	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0031965	nuclear membrane	GAPDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GAPDH	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	GAPDH	IDA		Human	PMID:28404743
Cellular Component	GO:0005634	nucleus	Gapdh	IDA		Rat	PMID:15942958\|RGD:1598733
Cellular Component	GO:0005634	nucleus	Gapdh	IDA		Rat	PMID:15951807\|RGD:8554488
Cellular Component	GO:0005634	nucleus	Gapdh	IDA		Rat	PMID:19607794\|RGD:8553565
Cellular Component	GO:0005634	nucleus	Gapdh	IDA		Rat	PMID:20972425\|RGD:8554381
Cellular Component	GO:0005886	plasma membrane	GAPDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Gapdh	IDA		Mouse	PMID:18698006
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Gapdh	IDA		Rat	PMID:9371836\|RGD:13702148
Cellular Component	GO:1990904	ribonucleoprotein complex	GAPDH	IDA		Human	PMID:15479637
Cellular Component	GO:0031982	vesicle	GAPDH	HDA		Human	PMID:19190083
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0006915	apoptotic process	Gapdh	IMP		Rat	PMID:10424669\|RGD:632777
Biological Process	GO:0019933	cAMP-mediated signaling	Gapdh	IMP		Rat	PMID:28258188\|RGD:13792662
Biological Process	GO:0061621	canonical glycolysis	Gapdh	IMP		Mouse	PMID:28918937
Biological Process	GO:0061621	canonical glycolysis	Gapdh	IMP		Mouse	PMID:10777777
Biological Process	GO:0061621	canonical glycolysis	Gapdh	IDA		Mouse	PMID:12581789
Biological Process	GO:0005975	carbohydrate metabolic process	Gapdh	IDA		Rat	PMID:1834654\|RGD:1599371
Biological Process	GO:0071346	cellular response to type II interferon	GAPDH	IDA		Human	PMID:15479637
Biological Process	GO:0050832	defense response to fungus	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0007565	female pregnancy	Gapdh	IEP		Rat	PMID:27312951\|RGD:13792674
Biological Process	GO:0006094	gluconeogenesis	Gapdh	IDA		Mouse	PMID:28258188
Biological Process	GO:0006094	gluconeogenesis	Gapdh	IDA		Rat	PMID:15720133\|RGD:2302795
Biological Process	GO:0006094	gluconeogenesis	Gapdh	IMP		Rat	PMID:28258188\|RGD:13792662
Biological Process	GO:0006096	glycolytic process	Gapdh	IMP		Rat	PMID:28258188\|RGD:13792662
Biological Process	GO:0051873	killing by host of symbiont cells	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0031640	killing of cells of another organism	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0000226	microtubule cytoskeleton organization	Gapdh	IDA		Rat	PMID:15312048\|RGD:8553423
Biological Process	GO:0007275	multicellular organism development	Gapdh	IMP	MGI:MGI:2183515	Mouse	PMID:3796661
Biological Process	GO:0010951	negative regulation of endopeptidase activity	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0017148	negative regulation of translation	GAPDH	IMP		Human	PMID:15479637
Biological Process	GO:0017148	negative regulation of translation	GAPDH	IDA		Human	PMID:23071094
Biological Process	GO:0017148	negative regulation of translation	Gapdh	IDA		Mouse	MGI:MGI:5466658\|PMID:23071094
Biological Process	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process	Gapdh	IMP		Rat	PMID:28404743\|RGD:13792653
Biological Process	GO:0051402	neuron apoptotic process	Gapdh	IMP		Rat	PMID:15951807\|RGD:8554488
Biological Process	GO:0051402	neuron apoptotic process	Gapdh	IDA		Rat	PMID:19607794\|RGD:8553565
Biological Process	GO:0035606	peptidyl-cysteine S-trans-nitrosylation	Gapdh	IDA		Rat	PMID:20972425\|RGD:8554381
Biological Process	GO:0001819	positive regulation of cytokine production	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	GAPDH	IDA		Human	PMID:23332158
Biological Process	GO:0032481	positive regulation of type I interferon production	GAPDH	IDA		Human	PMID:27387501
Biological Process	GO:0050821	protein stabilization	Gapdh	IDA		Rat	PMID:15951807\|RGD:8554488

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.