Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GALR2
  • Mouse genes Galr2
  • Rat genes Galr2
  • Zfish genes galr2a,galr2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Galr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004966	galanin receptor activity	GALR2	IDA		Human	PMID:24517231
Molecular Function	GO:0004966	galanin receptor activity	GALR2	IDA		Human	PMID:9832121
Molecular Function	GO:0004966	galanin receptor activity	Galr2	IMP		Rat	PMID:17143559|RGD:1625746
Molecular Function	GO:0004966	galanin receptor activity	Galr2	IDA		Rat	PMID:9305929|RGD:69841
Molecular Function	GO:0004966	galanin receptor activity	Galr2	IDA		Rat	PMID:9427506|RGD:69840
Molecular Function	GO:0004966	galanin receptor activity	Galr2	IDA		Rat	PMID:9578554|RGD:2303421
Molecular Function	GO:0004966	galanin receptor activity	galr2a	IDA		Zfish	PMID:24517231
Molecular Function	GO:0004966	galanin receptor activity	galr2b	IDA		Zfish	PMID:24517231
Molecular Function	GO:0042923	neuropeptide binding	Galr2	IMP		Rat	PMID:17143559|RGD:1625746
Molecular Function	GO:0042923	neuropeptide binding	Galr2	IDA		Rat	PMID:9305929|RGD:69841
Molecular Function	GO:0042923	neuropeptide binding	Galr2	IDA		Rat	PMID:9427506|RGD:69840
Molecular Function	GO:0042923	neuropeptide binding	Galr2	IDA		Rat	PMID:9578554|RGD:2303421
Molecular Function	GO:0017046	peptide hormone binding	GALR2	IDA		Human	PMID:24517231
Molecular Function	GO:0017046	peptide hormone binding	GALR2	IPI	CHEBI:80161	Human	PMID:9832121
Molecular Function	GO:0005515	protein binding	GALR2	IPI	UniProtKB:P22466:PRO_0000010449	Human	PMID:23597562
Molecular Function	GO:0005515	protein binding	GALR2	IPI	UniProtKB:P22466	Human	PMID:25691535
Cellular Component	GO:0005929	cilium	GALR2	IDA		Human	PMID:28154160
Cellular Component	GO:0005886	plasma membrane	Galr2	IDA		Rat	PMID:15471987|RGD:2303425
Cellular Component	GO:0005886	plasma membrane	Galr2	IDA		Rat	PMID:9305929|RGD:69841
Cellular Component	GO:0005886	plasma membrane	Galr2	IDA		Rat	PMID:9578554|RGD:2303421
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Galr2	IMP		Rat	PMID:17143559|RGD:1625746
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Galr2	IDA		Rat	PMID:9578554|RGD:2303421
Biological Process	GO:0090663	galanin-activated signaling pathway	GALR2	IDA		Human	PMID:9832121
Biological Process	GO:0043647	inositol phosphate metabolic process	Galr2	IDA		Rat	PMID:9427506|RGD:69840
Biological Process	GO:0031175	neuron projection development	Galr2	IDA		Mouse	PMID:12533601
Biological Process	GO:0007218	neuropeptide signaling pathway	galr2a	IDA		Zfish	PMID:24517231|ZFIN:ZDB-PUB-140502-2
Biological Process	GO:0007218	neuropeptide signaling pathway	galr2b	IDA		Zfish	PMID:24517231|ZFIN:ZDB-PUB-140502-2
Biological Process	GO:0046488	phosphatidylinositol metabolic process	Galr2	IDA		Rat	PMID:9305929|RGD:69841
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	GALR2	IDA		Human	PMID:9832121
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Galr2	IDA		Rat	PMID:15471987|RGD:2303425
Biological Process	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity	GALR2	IMP		Human	PMID:24602615
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GALR2	IDA		Human	PMID:24517231

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern