About   Help   FAQ
Galr2
Gene Detail
 Symbol
Name
ID
Galr2
galanin receptor 2
MGI:1337018
Synonyms GalR2, mGalR
Feature Type protein coding gene
Genetic Map
Chromosome 11
81.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:116280939-116283938 bp, + strand
From VEGA annotation of GRCm38

  3000 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2863  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: galanin receptor
Gene Tree: Galr2

Human
homologs
Human Homolog GALR2, galanin receptor 2
NCBI Gene ID 8811
neXtProt AC  NX_O43603
Human Synonyms  GAL2-R, GALNR2, GALR-2
Human Chr (Location)  17q25.3; chr17:76074801-76077541 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display a reduction in exploratory activity. There is also a modest shift in the distribution of different lymphocyte cell types.
 
Interactions
Galr2 interacts with 30 markers (Mir10a, Mir10b, Mir129-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process G-protein coupled receptor signaling pathway, negative regulation of adenylate cyclase activity, ...
Component integral component of membrane, membrane, ...
Function galanin receptor activity, G-protein coupled receptor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000003839 (Evidence)
Ensembl Gene ModelENSMUSG00000020793 (Evidence)
Entrez Gene14428 (Evidence)
UniGene57149
DFCITC1589509
DoTSDT.55245103, DT.87033475
NIA Mouse Gene IndexU013569
Consensus CDS ProjectCCDS25663.1
International Mouse Knockout Project StatusGalr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003839 VEGA Gene Model | MGI Sequence Detail 3000 C57BL/6J ±  kb
transcript OTTMUST00000008433 VEGA | MGI Sequence Detail 1940 Not Applicable 
polypeptide OTTMUSP00000004088 VEGA | MGI Sequence Detail 371 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(59 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003907 Galanin receptor 2
InterPro IPR000405 Galanin receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001586 galanin receptor type 2
References (Earliest) J:51042 Pang L, et al., The mouse GalR2 galanin receptor: genomic organization, cDNA cloning, and functional characterization. J Neurochem. 1998 Dec;71(6):2252-9
(Latest) J:185665 Guo Z, et al., Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
All references(45)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory