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Galr2
Gene Detail
Symbol

Name
ID
Galr2
galanin receptor 2
MGI:1337018
Synonyms
GalR2, mGalR
Feature Type
protein coding gene
Genetic Map
Chromosome 11
81.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:116280939-116283938 bp, + strand
From VEGA annotation of GRCm38

  3000 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2863  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GALR2
Protein SuperFamily: galanin receptor
Gene Tree: Galr2

Human
homologs
GALR2, galanin receptor 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 8811
neXtProt AC: NX_O43603

Human Synonyms: GAL2-R, GALNR2, GALR-2

Human Chr (Location): 17q25.3; chr17:76072088-76077541 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display a reduction in exploratory activity. There is also a modest shift in the distribution of different lymphocyte cell types.
 
Interactions
Galr2 interacts with 30 markers (Mir10a, Mir10b, Mir129-1, ...)
Expression
Literature Summary: (1 records)
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000003839 (Evidence)
Ensembl Gene Model ENSMUSG00000020793 (Evidence)
Entrez Gene 14428 (Evidence)
UniGene 57149
DFCI TC1589509
DoTS DT.87033475, DT.55245103
NIA Mouse Gene Index U013569
Consensus CDS Project CCDS25663.1
International Mouse Phenotyping Consortium Status Galr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003839 VEGA Gene Model | MGI Sequence Detail 3000 C57BL/6J ±  kb
transcript OTTMUST00000008433 VEGA | MGI Sequence Detail 1940 Not Applicable 
polypeptide OTTMUSP00000004088 VEGA | MGI Sequence Detail 371 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(9) UniProt(2)
Polymorphisms
SNPs within 2kb(59 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003907 Galanin receptor 2
InterPro IPR000405 Galanin receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001586 galanin receptor type 2
References
(Earliest) J:51042 Pang L, et al., The mouse GalR2 galanin receptor: genomic organization, cDNA cloning, and functional characterization. J Neurochem. 1998 Dec;71(6):2252-9
(Latest) J:214920 Einstein EB, et al., Galanin-induced decreases in nucleus accumbens/striatum excitatory postsynaptic potentials and morphine conditioned place preference require both galanin receptor 1 and galanin receptor 2. Eur J Neurosci. 2013 May;37(9):1541-9
All references(46)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory