Galr2
Gene Detail

Symbol Name ID

Galr2 galanin receptor 2 MGI:1337018

Synonyms

GalR2, mGalR

Feature Type

protein coding gene

Genetic Map

Chromosome 11

81.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr11:116280939-116283938 bp, + strand From VEGA annotation of GRCm38   3000 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Galr2 ± 2 cM)

Protein SuperFamily: galanin receptor
Gene Tree: Galr2

Human ortholog

GALR2 galanin receptor 2 NCBI Gene ID 8811
Human Synonyms: GALNR2
Human Chr17:74070892-74073573 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(9) : Targeted(4) Gene trapped(5)
 

Mice homozygous for disruptions in this gene display a reduction in exploratory activity. There is also a modest shift in the distribution of different lymphocyte cell types.

 

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	adenylate cyclase-activating G-protein coupled receptor signaling pathway, elevation of cytosolic calcium ion concentration, ...
Component	integral to membrane, membrane, ...
Function	galanin receptor activity, G-protein coupled receptor activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(5)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000003839 (Evidence)
Ensembl Gene Model	ENSMUSG00000020793 (Evidence)
Entrez Gene	14428 (Evidence)
UniGene	57149
DFCI	TC1589509
DoTS	DT.55245103, DT.87033475
NIA Mouse Gene Index	U013569
Consensus CDS Project	CCDS25663.1
International Mouse Knockout Project Status	Galr2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000003839	VEGA Gene Model | MGI Sequence Detail	3000	C57BL/6J
transcript	OTTMUST00000008433	VEGA | MGI Sequence Detail	1940	Not Applicable
polypeptide	OTTMUSP00000004088	VEGA | MGI Sequence Detail	371	Not Applicable

All sequences(25) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(16 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003907	Galanin 2 receptor
InterPro	IPR000405	Galanin receptor
InterPro	IPR000276	GPCR, rhodopsin-like
InterPro	IPR017452	GPCR, rhodopsin-like, 7TM
Protein Ontology	PR:000001586	galanin receptor 2

References

(Earliest) J:51042 Pang L, et al., The mouse GalR2 galanin receptor: genomic organization, cDNA cloning, and functional characterization. J Neurochem. 1998 Dec;71(6):2252-9
(Latest) J:185665 Guo Z, et al., Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
All references(44)