Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GAB1
  • Mouse genes Gab1
  • Rat genes Gab1
  • Zfish genes gab1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gab1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P27986	Human	PMID:10978177
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:11323411
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:11453982
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q12913	Human	PMID:12475979
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:12855672
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P49023	Human	PMID:14665621
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:14665621
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:14701753
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P20936	Human	PMID:15574420
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:15574420
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:15985432
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P27986	Human	PMID:16638574
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q12913	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P62993	Human	PMID:19380743
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:20308328
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P62993	Human	PMID:20473329
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:20473329
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P62993	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P00533	Human	PMID:21278788
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P62993	Human	PMID:22536782
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P46109	Human	PMID:23397142
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:O00459	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:O14543	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:O14544	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:O14796	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:O15357	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:O43639	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P06239	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P07332	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P07947	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P07948	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P12931	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P15498	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P16333	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P16885	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P19174	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P20936	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P27986	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P29353	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P42680	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P43405	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P46108	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P46109	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P51451	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P52735	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q13882	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q92569	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q9H6Q3	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q9NP31	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q9UKW4	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q9ULZ2	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124-2	Human	PMID:24935154
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P46109	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q9UNN4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q8N6R0	Human	PMID:29408807
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P46109	Human	PMID:31585087
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P50904	Human	PMID:31585087
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P62993	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P00533	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:P27986	Human	PMID:9658397
Molecular Function	GO:0005515	protein binding	GAB1	IPI	UniProtKB:Q06124	Human	PMID:9658397
Molecular Function	GO:0005515	protein binding	Gab1	IPI	UniProtKB:Q60631	Mouse	MGI:MGI:5553227|PMID:23452850
Molecular Function	GO:0005515	protein binding	Gab1	IPI	UniProtKB:Q60631	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Gab1	IPI	UniProtKB:Q60631	Mouse	MGI:MGI:5508295|PMID:10871282
Molecular Function	GO:0005515	protein binding	Gab1	IPI	UniProtKB:Q60631	Mouse	MGI:MGI:3768200|PMID:11445578
Molecular Function	GO:0005515	protein binding	Gab1	IPI	UniProtKB:F1N339|UniProtKB:P08487|UniProtKB:Q0IIE2	Mouse	MGI:MGI:6094554|PMID:17178724
Molecular Function	GO:0005515	protein binding	Gab1	IPI	UniProtKB:F1MWF1	Mouse	MGI:MGI:6094554|PMID:17178724
Molecular Function	GO:0005515	protein binding	Gab1	IPI	RGD:2405	Rat	PMID:16187300|RGD:1642619
Molecular Function	GO:0035591	signaling adaptor activity	Gab1	IDA		Mouse	PMID:15273746
Molecular Function	GO:0035591	signaling adaptor activity	Gab1	IMP	MGI:MGI:3759868	Mouse	PMID:17881575
Cellular Component	GO:0005911	cell-cell junction	GAB1	IMP		Human	PMID:26706435
Cellular Component	GO:0005737	cytoplasm	Gab1	IDA		Mouse	PMID:15736129
Biological Process	GO:0031532	actin cytoskeleton reorganization	GAB1	IMP		Human	PMID:17178724
Biological Process	GO:0001525	angiogenesis	GAB1	IMP		Human	PMID:17178724
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	Gab1	IDA		Mouse	MGI:MGI:6094554|PMID:17178724
Biological Process	GO:0090668	endothelial cell chemotaxis to vascular endothelial growth factor	GAB1	IMP		Human	PMID:17178724
Biological Process	GO:0090504	epiboly	gab1	IMP	ZFIN:ZDB-MRPHLNO-180828-2	Zfish	PMID:29408807
Biological Process	GO:0090504	epiboly	gab1	IMP	ZFIN:ZDB-MRPHLNO-180828-1	Zfish	PMID:29408807
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Gab1	IMP	MGI:MGI:3759868	Mouse	PMID:17881575
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Gab1	IMP	MGI:MGI:1926435	Mouse	PMID:10779359
Biological Process	GO:0008544	epidermis development	Gab1	IMP	MGI:MGI:1926435	Mouse	PMID:10779359
Biological Process	GO:0007507	heart development	Gab1	IMP	MGI:MGI:1926435	Mouse	PMID:10779359
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	Gab1	IMP	MGI:MGI:1926435	Mouse	PMID:10779359
Biological Process	GO:0060711	labyrinthine layer development	Gab1	IMP	MGI:MGI:1926435	Mouse	PMID:10779359
Biological Process	GO:0000165	MAPK cascade	Gab1	IMP	MGI:MGI:1926435	Mouse	PMID:10779359
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Gab1	IMP	MGI:MGI:1926435	Mouse	PMID:10779359
Biological Process	GO:0045766	positive regulation of angiogenesis	GAB1	IMP		Human	PMID:25217442
Biological Process	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway	Gab1	IDA		Mouse	MGI:MGI:6094554|PMID:17178724
Biological Process	GO:0043406	positive regulation of MAP kinase activity	Gab1	IMP	MGI:MGI:2667211	Mouse	PMID:12808090
Biological Process	GO:0043410	positive regulation of MAPK cascade	Gab1	IDA		Mouse	PMID:11940581
Biological Process	GO:0043410	positive regulation of MAPK cascade	Gab1	IMP	MGI:MGI:1926435	Mouse	PMID:10779359
Biological Process	GO:0030334	regulation of cell migration	Gab1	IGI	MGI:MGI:109563	Mouse	PMID:16166380
Biological Process	GO:0035728	response to hepatocyte growth factor	Gab1	IPI	RGD:2405	Rat	PMID:16187300|RGD:1642619
Biological Process	GO:0006979	response to oxidative stress	Gab1	IDA		Mouse	PMID:12808090
Biological Process	GO:0007165	signal transduction	Gab1	IDA		Mouse	PMID:11940581
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	GAB1	IMP		Human	PMID:17178724

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern