Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FSHB
  • Mouse genes Fshb
  • Rat genes Fshb
  • Zfish genes fshb,lhb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fshb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016913	follicle-stimulating hormone activity	FSHB	IMP		Human	PMID:11514332
Molecular Function	GO:0016913	follicle-stimulating hormone activity	FSHB	IDA		Human	PMID:24692546
Molecular Function	GO:0016913	follicle-stimulating hormone activity	FSHB	IDA		Human	PMID:2494176
Molecular Function	GO:0005179	hormone activity	fshb	IDA		Zfish	PMID:15728795
Molecular Function	GO:0005179	hormone activity	lhb	IDA		Zfish	PMID:15728795
Molecular Function	GO:0005515	protein binding	FSHB	IPI	UniProtKB:P01215	Human	PMID:11222739
Molecular Function	GO:0005515	protein binding	FSHB	IPI	UniProtKB:P01215	Human	PMID:15662415
Molecular Function	GO:0005515	protein binding	FSHB	IPI	UniProtKB:P01215	Human	PMID:22802634
Cellular Component	GO:0005737	cytoplasm	FSHB	IDA		Human	PMID:14602737
Cellular Component	GO:0005737	cytoplasm	Fshb	IDA		Mouse	PMID:24739304
Cellular Component	GO:0005615	extracellular space	FSHB	IDA		Human	PMID:24692546
Cellular Component	GO:0005615	extracellular space	FSHB	IDA		Human	PMID:2494176
Cellular Component	GO:0016914	follicle-stimulating hormone complex	FSHB	IPI		Human	PMID:11222739
Cellular Component	GO:0016914	follicle-stimulating hormone complex	FSHB	IDA		Human	PMID:24692546
Cellular Component	GO:0016914	follicle-stimulating hormone complex	FSHB	IDA		Human	PMID:2494176
Biological Process	GO:0008585	female gonad development	fshb	IMP	ZFIN:ZDB-GENO-170306-1	Zfish	PMID:26452104
Biological Process	GO:0008585	female gonad development	fshb	IGI	ZFIN:ZDB-GENE-040806-2	Zfish	PMID:26452104
Biological Process	GO:0008585	female gonad development	lhb	IGI	ZFIN:ZDB-GENE-040806-1	Zfish	PMID:26452104
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	Fshb	IMP	MGI:MGI:1857434	Mouse	PMID:9020850
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	FSHB	IDA		Human	PMID:24692546
Biological Process	GO:0001556	oocyte maturation	lhb	IMP	ZFIN:ZDB-GENO-201007-1	Zfish	PMID:31322169
Biological Process	GO:0001556	oocyte maturation	lhb	IMP	ZFIN:ZDB-GENO-150429-3	Zfish	PMID:25396299
Biological Process	GO:0001556	oocyte maturation	lhb	IMP	ZFIN:ZDB-GENO-160127-5	Zfish	PMID:25584412
Biological Process	GO:0001556	oocyte maturation	lhb	IMP	ZFIN:ZDB-GENO-160127-1	Zfish	PMID:25238195
Biological Process	GO:0001541	ovarian follicle development	Fshb	IMP	MGI:MGI:1857434	Mouse	PMID:9020850
Biological Process	GO:0001541	ovarian follicle development	fshb	IMP	ZFIN:ZDB-GENO-150429-2	Zfish	PMID:25396299
Biological Process	GO:0001541	ovarian follicle development	fshb	IMP	ZFIN:ZDB-GENO-170306-1	Zfish	PMID:26452104
Biological Process	GO:0030728	ovulation	lhb	IMP	ZFIN:ZDB-GENO-150429-3	Zfish	PMID:25396299
Biological Process	GO:0030728	ovulation	lhb	IMP	ZFIN:ZDB-GENO-160127-1	Zfish	PMID:25238195
Biological Process	GO:0045780	positive regulation of bone resorption	Fshb	IMP	MGI:MGI:1857434	Mouse	PMID:16630814
Biological Process	GO:0010628	positive regulation of gene expression	Fshb	IDA		Mouse	PMID:23242526
Biological Process	GO:0010893	positive regulation of steroid biosynthetic process	FSHB	IDA		Human	PMID:2494176
Biological Process	GO:0045670	regulation of osteoclast differentiation	Fshb	IMP	MGI:MGI:1857434	Mouse	PMID:16630814
Biological Process	GO:0010469	regulation of signaling receptor activity	FSHB	IDA		Human	PMID:24692546
Biological Process	GO:0060011	Sertoli cell proliferation	Fshb	IMP	MGI:MGI:1857434	Mouse	PMID:11416011
Biological Process	GO:0007530	sex determination	fshb	IGI	ZFIN:ZDB-GENE-040806-2	Zfish	PMID:25396299
Biological Process	GO:0007530	sex determination	fshb	IMP	ZFIN:ZDB-GENO-150429-2	Zfish	PMID:25396299
Biological Process	GO:0007530	sex determination	lhb	IGI	ZFIN:ZDB-GENE-040806-1	Zfish	PMID:25396299
Biological Process	GO:0007283	spermatogenesis	Fshb	IGI	MGI:MGI:102806	Mouse	PMID:11459797
Biological Process	GO:0007283	spermatogenesis	fshb	IGI	ZFIN:ZDB-GENE-040806-2	Zfish	PMID:26452104
Biological Process	GO:0007283	spermatogenesis	lhb	IGI	ZFIN:ZDB-GENE-040806-1	Zfish	PMID:26452104
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	FSHB	IEP		Human	PMID:14557487

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern