Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FPR1
  • Mouse genes Fpr1
  • Rat genes Fpr1
  • Zfish genes fpr1,si:ch211-137j23.9,si:ch73-160i9.1,si:ch73-160i9.2,si:dkey-211g8.1,si:dkey-42l23.4,si:dkey-42l23.5,si:dkey-42l23.7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fpr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	FPR1	IDA		Human	PMID:15210802
Molecular Function	GO:0001664	G protein-coupled receptor binding	FPR1	IDA		Human	PMID:10823817
Molecular Function	GO:0004982	N-formyl peptide receptor activity	FPR1	IDA		Human	PMID:12218158
Molecular Function	GO:0004982	N-formyl peptide receptor activity	FPR1	IDA		Human	PMID:22859307
Molecular Function	GO:0004982	N-formyl peptide receptor activity	Fpr1	IDA		Mouse	PMID:22859307
Molecular Function	GO:0005515	protein binding	FPR1	IPI	UniProtKB:O15264	Human	PMID:22447027
Molecular Function	GO:0005515	protein binding	FPR1	IPI	UniProtKB:P25098	Human	PMID:22447027
Molecular Function	GO:0050786	RAGE receptor binding	Fpr1	IPI	RGD:69258	Rat	PMID:23164356|RGD:7244287
Molecular Function	GO:0005124	scavenger receptor binding	Fpr1	IPI	UniProtKB:M0R9F7	Rat	PMID:20141570|RGD:12907556
Cellular Component	GO:0005737	cytoplasm	Fpr1	IDA		Rat	PMID:20141570|RGD:12907556
Cellular Component	GO:0005886	plasma membrane	Fpr1	IDA		Rat	PMID:20141570|RGD:12907556
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Fpr1	IDA		Mouse	PMID:12470609
Biological Process	GO:0002283	neutrophil activation involved in immune response	fpr1	IMP	ZFIN:ZDB-MRPHLNO-121227-1	Zfish	PMID:22980327
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	FPR1	IDA		Human	PMID:22859307
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Fpr1	IDA		Mouse	PMID:22859307

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern