Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXO2
  • Mouse genes Fbxo2
  • Rat genes Fbxo2
  • Zfish genes fbxo2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxo2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	Fbxo2	IDA		Mouse	PMID:9173930
Molecular Function	GO:0030246	carbohydrate binding	Fbxo2	IDA		Mouse	PMID:12939278
Molecular Function	GO:0031249	denatured protein binding	Fbxo2	IDA		Mouse	PMID:15723043
Molecular Function	GO:0005515	protein binding	FBXO2	IPI	UniProtKB:P63208	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXO2	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	FBXO2	IPI	UniProtKB:O15212	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXO2	IPI	UniProtKB:P63208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXO2	IPI	UniProtKB:Q3KNR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXO2	IPI	UniProtKB:Q6UX27-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fbxo2	IPI	UniProtKB:P61823|UniProtKB:P63208-1	Mouse	MGI:MGI:6092692|PMID:17389369
Molecular Function	GO:0005515	protein binding	Fbxo2	IPI	PR:P09055	Mouse	PMID:15723043
Molecular Function	GO:0005515	protein binding	Fbxo2	IPI	PR:Q01853	Mouse	PMID:15723043
Molecular Function	GO:0005515	protein binding	Fbxo2	IPI	PR:P35438	Mouse	PMID:15809437
Cellular Component	GO:0005737	cytoplasm	FBXO2	IDA		Human	PMID:21378169
Cellular Component	GO:0005829	cytosol	Fbxo2	IDA		Mouse	MGI:MGI:4821082|PMID:12140560
Cellular Component	GO:0043197	dendritic spine	Fbxo2	IDA		Mouse	PMID:15809437
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	Fbxo2	IDA		Rat	PMID:15809437|RGD:155230778
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	Fbxo2	IMP		Rat	PMID:15809437|RGD:155230778
Cellular Component	GO:0098978	glutamatergic synapse	Fbxo2	IDA		Mouse	PMID:15809437
Cellular Component	GO:0098978	glutamatergic synapse	Fbxo2	IMP		Mouse	PMID:15809437
Cellular Component	GO:0098978	glutamatergic synapse	Fbxo2	IPI		Mouse	PMID:15809437
Cellular Component	GO:0098978	glutamatergic synapse	Fbxo2	IDA		Rat	PMID:15809437|RGD:155230778
Cellular Component	GO:0098978	glutamatergic synapse	Fbxo2	IMP		Rat	PMID:15809437|RGD:155230778
Cellular Component	GO:0098794	postsynapse	Fbxo2	IDA		Mouse	MGI:MGI:3576440|PMID:15809437
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	Fbxo2	IDA		Mouse	MGI:MGI:4821082|PMID:12140560
Biological Process	GO:0006516	glycoprotein catabolic process	Fbxo2	IDA		Mouse	MGI:MGI:4821082|PMID:12140560
Biological Process	GO:0006516	glycoprotein catabolic process	Fbxo2	IDA		Mouse	PMID:15723043
Biological Process	GO:0008285	negative regulation of cell population proliferation	Fbxo2	IDA		Rat	PMID:9857061|RGD:632756
Biological Process	GO:0016567	protein ubiquitination	Fbxo2	IDA		Mouse	MGI:MGI:4821082|PMID:12140560
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	Fbxo2	IDA		Mouse	PMID:15809437
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	Fbxo2	IMP		Mouse	PMID:15809437
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	Fbxo2	IPI		Mouse	PMID:15809437
Biological Process	GO:0031396	regulation of protein ubiquitination	Fbxo2	IDA		Mouse	PMID:15809437
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Fbxo2	IDA		Mouse	MGI:MGI:4821082|PMID:12140560
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	Fbxo2	IDA		Mouse	PMID:15723043
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Fbxo2	IDA		Mouse	PMID:15723043

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern