Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Fasn

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FASN
- Mouse genes Fasn
- Rat genes Fasn
- Zfish genes ccdc57,fasn
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fasn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity	Fasn	IMP		Rat	PMID:8940200\|RGD:15090840
Molecular Function	GO:0045296	cadherin binding	FASN	HDA		Human	PMID:25468996
Molecular Function	GO:0004312	fatty acid synthase activity	Fasn	IDA		Mouse	PMID:16054098
Molecular Function	GO:0004312	fatty acid synthase activity	Fasn	IMP	MGI:MGI:3765071	Mouse	PMID:16054078
Molecular Function	GO:0004312	fatty acid synthase activity	Fasn	IDA		Mouse	PMID:22331133
Molecular Function	GO:0004312	fatty acid synthase activity	Fasn	IDA		Rat	PMID:15715522\|RGD:2317317
Molecular Function	GO:0004312	fatty acid synthase activity	Fasn	IDA		Rat	PMID:18062843\|RGD:2317315
Molecular Function	GO:0004312	fatty acid synthase activity	Fasn	IDA		Rat	PMID:21389266\|RGD:10047361
Molecular Function	GO:0004312	fatty acid synthase activity	Fasn	IDA		Rat	PMID:21569266\|RGD:10047183
Molecular Function	GO:0042802	identical protein binding	Fasn	IPI	UniProtKB:P12785	Rat	PMID:10206962\|RGD:8554616
Molecular Function	GO:0042802	identical protein binding	Fasn	IPI	UniProtKB:P12785	Rat	PMID:11248039\|RGD:5129740
Molecular Function	GO:0042802	identical protein binding	Fasn	IPI	UniProtKB:P12785	Rat	PMID:15711565\|RGD:8554436
Molecular Function	GO:0042802	identical protein binding	Fasn	IPI	RGD:620665	Rat	PMID:19151726\|RGD:2317324
Molecular Function	GO:0042802	identical protein binding	Fasn	IPI	UniProtKB:P12785	Rat	PMID:19151726\|RGD:2317324
Molecular Function	GO:0042802	identical protein binding	Fasn	IPI	UniProtKB:P12785	Rat	PMID:9047334\|RGD:8554123
Molecular Function	GO:0005515	protein binding	FASN	IPI	UniProtKB:Q9NRN7	Human	PMID:18022563
Molecular Function	GO:0005515	protein binding	FASN	IPI	UniProtKB:Q99IB8:PRO_0000045603	Human	PMID:23427160
Molecular Function	GO:0005515	protein binding	FASN	IPI	UniProtKB:P42858	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	FASN	IPI	UniProtKB:Q8IV20	Human	PMID:27478939
Molecular Function	GO:0005515	protein binding	FASN	IPI	UniProtKB:Q15848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FASN	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FASN	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Fasn	IPI	UniProtKB:P16573	Rat	PMID:16054098\|RGD:11059593
Molecular Function	GO:0003723	RNA binding	FASN	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	FASN	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	Fasn	IDA		Rat	PMID:16054098\|RGD:11059593
Cellular Component	GO:0005737	cytoplasm	Fasn	IDA		Rat	PMID:22023808\|RGD:153297778
Cellular Component	GO:0005737	cytoplasm	Fasn	IDA		Rat	PMID:29504286\|RGD:152995491
Cellular Component	GO:0005829	cytosol	FASN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	FASN	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	FASN	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	FASN	HDA		Human	PMID:23533145
Cellular Component	GO:0042587	glycogen granule	Fasn	IDA		Mouse	PMID:15169678
Cellular Component	GO:0005794	Golgi apparatus	FASN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	FASN	HDA		Human	PMID:16210410
Cellular Component	GO:0016020	membrane	FASN	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Fasn	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005886	plasma membrane	FASN	IDA		Human	GO_REF:0000052
Biological Process	GO:0006084	acetyl-CoA metabolic process	Fasn	IDA		Rat	PMID:18062843\|RGD:2317315
Biological Process	GO:0071353	cellular response to interleukin-4	Fasn	IDA		Mouse	PMID:9798653
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	Fasn	IMP	MGI:MGI:3765070	Mouse	PMID:25565205
Biological Process	GO:0008611	ether lipid biosynthetic process	Fasn	IMP	MGI:MGI:3765070	Mouse	PMID:25565205
Biological Process	GO:0006633	fatty acid biosynthetic process	Fasn	IDA		Mouse	PMID:22331133
Biological Process	GO:0006633	fatty acid biosynthetic process	Fasn	IDA		Rat	PMID:15715522\|RGD:2317317
Biological Process	GO:0002068	glandular epithelial cell development	Fasn	IMP	MGI:MGI:3765070	Mouse	PMID:25565205
Biological Process	GO:0006954	inflammatory response	Fasn	IMP	MGI:MGI:3765070	Mouse	PMID:25565205
Biological Process	GO:0008610	lipid biosynthetic process	Fasn	IDA		Mouse	PMID:16054098
Biological Process	GO:0008610	lipid biosynthetic process	Fasn	IMP	MGI:MGI:3765071	Mouse	PMID:16054078
Biological Process	GO:0030879	mammary gland development	Fasn	IMP		Mouse	MGI:MGI:5582996\|PMID:24668799
Biological Process	GO:0044788	modulation by host of viral process	FASN	IDA		Human	PMID:34320401
Biological Process	GO:0030224	monocyte differentiation	Fasn	IMP	MGI:MGI:3765070	Mouse	PMID:25565205
Biological Process	GO:0030223	neutrophil differentiation	Fasn	IMP	MGI:MGI:3765070	Mouse	PMID:25565205
Biological Process	GO:0001649	osteoblast differentiation	FASN	HDA		Human	PMID:16210410
Biological Process	GO:0061959	response to (R)-carnitine	fasn	IEP		Zfish	PMID:28102299
Biological Process	GO:0031667	response to nutrient levels	Fasn	IEP		Rat	PMID:25943649\|RGD:152995488
Biological Process	GO:0009888	tissue development	Fasn	IMP	MGI:MGI:3765070	Mouse	PMID:25565205

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.