Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ENO2
  • Mouse genes Eno2
  • Rat genes Eno2
  • Zfish genes eno2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eno2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Eno2	IPI	UniProtKB:P04764	Rat	PMID:14499952|RGD:12793007
Molecular Function	GO:0019899	enzyme binding	Eno2	IPI	UniProtKB:P04764	Rat	PMID:15041191|RGD:2302788
Molecular Function	GO:0042802	identical protein binding	Eno2	IPI	RGD:2554	Rat	PMID:7086434|RGD:2302787
Molecular Function	GO:0042802	identical protein binding	Eno2	IPI	RGD:2554	Rat	PMID:990313|RGD:2293754
Molecular Function	GO:0004634	phosphopyruvate hydratase activity	Eno2	IDA		Rat	PMID:15720133|RGD:2302795
Molecular Function	GO:0004634	phosphopyruvate hydratase activity	Eno2	IDA		Rat	PMID:7964722|RGD:12792993
Molecular Function	GO:0005515	protein binding	ENO2	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0044877	protein-containing complex binding	Eno2	IDA		Rat	PMID:15041191|RGD:2302788
Molecular Function	GO:0044877	protein-containing complex binding	Eno2	IDA		Rat	PMID:7086434|RGD:2302787
Molecular Function	GO:0044877	protein-containing complex binding	Eno2	IDA		Rat	PMID:990313|RGD:2293754
Cellular Component	GO:0005938	cell cortex	Eno2	IDA		Rat	PMID:19433310|RGD:12792998
Cellular Component	GO:0009986	cell surface	Eno2	IDA		Rat	PMID:14499952|RGD:12793007
Cellular Component	GO:0009986	cell surface	Eno2	IDA		Rat	PMID:19433310|RGD:12792998
Cellular Component	GO:0005737	cytoplasm	Eno2	IDA		Mouse	PMID:9758704
Cellular Component	GO:0005737	cytoplasm	Eno2	IDA		Rat	PMID:110910|RGD:2293755
Cellular Component	GO:0005829	cytosol	ENO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	ENO2	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ENO2	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	ENO2	HDA		Human	PMID:22664934
Cellular Component	GO:0030426	growth cone	Eno2	IDA		Rat	PMID:19433310|RGD:12792998
Cellular Component	GO:0005622	intracellular anatomical structure	Eno2	IDA		Mouse	PMID:9671661
Cellular Component	GO:0016020	membrane	ENO2	IDA		Human	PMID:19433310
Cellular Component	GO:0045121	membrane raft	Eno2	IDA		Rat	PMID:14499952|RGD:12793007
Cellular Component	GO:0043209	myelin sheath	Eno2	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0043025	neuronal cell body	Eno2	IDA		Mouse	PMID:9364238
Cellular Component	GO:0043204	perikaryon	Eno2	IDA		Mouse	PMID:9671661
Cellular Component	GO:0000015	phosphopyruvate hydratase complex	Eno2	IDA		Rat	PMID:15041191|RGD:2302788
Cellular Component	GO:0001917	photoreceptor inner segment	Eno2	IDA		Mouse	PMID:9364238
Cellular Component	GO:0005886	plasma membrane	ENO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0097060	synaptic membrane	Eno2	IDA		Rat	PMID:15041191|RGD:2302788
Biological Process	GO:0061621	canonical glycolysis	Eno2	IDA		Rat	PMID:15041191|RGD:2302788
Biological Process	GO:0006094	gluconeogenesis	Eno2	IDA		Rat	PMID:15720133|RGD:2302795
Biological Process	GO:0048609	multicellular organismal reproductive process	Eno2	IEP		Rat	PMID:18511206|RGD:2293742
Biological Process	GO:1901215	negative regulation of neuron death	Eno2	IMP		Rat	PMID:19433310|RGD:12792998
Biological Process	GO:1901214	regulation of neuron death	Eno2	IGI	UniProtKB:Q9UBR2	Rat	PMID:19433310|RGD:12792998
Biological Process	GO:0032355	response to estradiol	Eno2	IEP		Rat	PMID:16689882|RGD:2293750
Biological Process	GO:0014070	response to organic cyclic compound	Eno2	IEP		Rat	PMID:15856951|RGD:2293752
Biological Process	GO:0009410	response to xenobiotic stimulus	Eno2	IEP		Rat	PMID:18289475|RGD:2293744

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern