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Eno2
Gene Detail
Symbol

Name
ID
Eno2
enolase 2, gamma neuronal
MGI:95394
Synonyms
D6Ertd375e, Eno-2, NSE
Feature Type
protein coding gene
Genetic Map
Chromosome 6
59.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr6:124760053-124769673 bp, - strand
From VEGA annotation of GRCm38

  9621 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74414  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: enolase
Gene Tree: Eno2

Human
homologs
Human Homolog ENO2, enolase 2 (gamma, neuronal)
NCBI Gene ID 2026
neXtProt AC  NX_P09104
Human Synonyms  HEL-S-279, NSE
Human Chr (Location)  12p13; chr12:6914450-6923696 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(1)
Interactions
Eno2 interacts with 156 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process glycolytic process
Component cytoplasm, extracellular space, ...
Function lyase activity, magnesium ion binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (36 records)
Data Summary: Results (316)    Tissues (180)    Images (53)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 5
RNA in situ 214
RT-PCR 97
cDNA source data(74)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(85) Genomic(4) cDNA(74) Primer pair(7)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000022240 (Evidence)
Ensembl Gene ModelENSMUSG00000004267 (Evidence)
Entrez Gene13807 (Evidence)
UniGene3913
DFCITC1572054, TC1618285, TC1686204
DoTSDT.101292868, DT.101386861, DT.101396376, DT.97337701, DT.97354926
NIA Mouse Gene IndexU027848
EC4.2.1.11
Consensus CDS ProjectCCDS20527.1
International Mouse Knockout Project StatusEno2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022240 VEGA Gene Model | MGI Sequence Detail 9621 C57BL/6J ±  kb
transcript OTTMUST00000052923 VEGA | MGI Sequence Detail 2795 Not Applicable 
polypeptide OTTMUSP00000025146 VEGA | MGI Sequence Detail 434 Not Applicable 

For the selected sequences
All sequences(85) RefSeq(8) UniProt(13)
Polymorphisms
SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000941 Enolase
InterPro IPR020809 Enolase, conserved site
InterPro IPR020810 Enolase, C-terminal
InterPro IPR020811 Enolase, N-terminal
Protein Ontology PR:000007081 gamma-enolase
References
(Earliest) J:8559 Lazar M, et al., Isolation of murine neuron-specific and non-neuronal enolase cDNA clones. Biochem Biophys Res Commun. 1986 Nov 26;141(1):271-7
(Latest) J:214076 Kobayashi Y, et al., Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice. Front Behav Neurosci. 2013;7:17
All references(82)
Other
accession IDs
MGD-MRK-9504, MGD-MRK-9507, MGI:1196312, MGI:2141477

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory