Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes E2F2
  • Mouse genes E2f2
  • Rat genes E2f2
  • Zfish genes e2f2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set E2f2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	E2F2	IDA		Human	PMID:15735762
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	E2F2	IDA		Human	PMID:7739537
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2f2	IDA		Mouse	PMID:11095619
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:P06400	Human	PMID:12502741
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:P06400	Human	PMID:16360038
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:Q14186	Human	PMID:16360038
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:Q5H9I0	Human	PMID:17062573
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:P06400	Human	PMID:17380128
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:Q14186	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:Q14186	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:Q14186	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	E2F2	IPI	UniProtKB:Q96C12	Human	PMID:28169274
Molecular Function	GO:0005515	protein binding	E2f2	IPI	PR:Q08639	Mouse	PMID:15448153
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	E2F2	IDA		Human	PMID:7739537
Molecular Function	GO:0043565	sequence-specific DNA binding	E2F2	IDA		Human	PMID:23332764
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	E2F2	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	E2f2	IDA		Mouse	PMID:10082561
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	E2F2	IDA		Human	PMID:7739537
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	E2f2	IDA		Mouse	PMID:11095619
Biological Process	GO:1990086	lens fiber cell apoptotic process	E2f2	IDA		Mouse	PMID:11095619
Biological Process	GO:1903671	negative regulation of sprouting angiogenesis	E2F2	IGI	RNAcentral:URS0000338542_9606	Human	PMID:27731397
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	E2F2	IDA		Human	PMID:7739537
Biological Process	GO:0051726	regulation of cell cycle	E2f2	IDA		Mouse	PMID:11095619
Biological Process	GO:0006355	regulation of DNA-templated transcription	E2f2	IDA		Mouse	PMID:11095619

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern