Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DUSP19
  • Mouse genes Dusp19
  • Rat genes Dusp19
  • Zfish genes dusp19a,dusp19b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dusp19

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008579	JUN kinase phosphatase activity	Dusp19	IDA		Mouse	PMID:11959861
Molecular Function	GO:0005078	MAP-kinase scaffold activity	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	Dusp19	IPI	UniProtKB:Q8CE90	Mouse	MGI:MGI:2182169|PMID:11959862
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	Dusp19	IPI	UniProtKB:Q99683	Mouse	MGI:MGI:2182169|PMID:11959862
Molecular Function	GO:0005515	protein binding	DUSP19	IPI	UniProtKB:P13196	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	DUSP19	IPI	UniProtKB:P13196	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DUSP19	IPI	UniProtKB:P13196	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DUSP19	IPI	UniProtKB:P60709	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DUSP19	IPI	UniProtKB:P13196	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DUSP19	IPI	UniProtKB:P60709	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dusp19	IPI	MGI:MGI:1346871	Mouse	PMID:11959861
Molecular Function	GO:0005515	protein binding	Dusp19	IPI	PR:O35099	Mouse	PMID:11959862
Molecular Function	GO:0030295	protein kinase activator activity	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Molecular Function	GO:0004860	protein kinase inhibitor activity	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	DUSP19	IDA		Human	PMID:12479873
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	Dusp19	IDA		Mouse	PMID:11432789
Molecular Function	GO:0008330	protein tyrosine/threonine phosphatase activity	Dusp19	IDA		Mouse	PMID:11959861
Cellular Component	GO:0005737	cytoplasm	Dusp19	IDA		Mouse	PMID:11959861
Biological Process	GO:0007254	JNK cascade	Dusp19	IDA		Mouse	PMID:11959862
Biological Process	GO:0046329	negative regulation of JNK cascade	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Biological Process	GO:0043508	negative regulation of JUN kinase activity	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Biological Process	GO:0043409	negative regulation of MAPK cascade	Dusp19	IDA		Mouse	PMID:11959861
Biological Process	GO:0006469	negative regulation of protein kinase activity	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Biological Process	GO:0046330	positive regulation of JNK cascade	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Biological Process	GO:0043410	positive regulation of MAPK cascade	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Biological Process	GO:0045860	positive regulation of protein kinase activity	Dusp19	IDA		Mouse	MGI:MGI:2182169|PMID:11959862
Biological Process	GO:0006470	protein dephosphorylation	Dusp19	IDA		Mouse	PMID:11959861

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern