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Dusp19 Gene Detail
Summary
  • Symbol
    Dusp19
  • Name
    dual specificity phosphatase 19
  • Synonyms
    5930436K22Rik, C79103, SKRP1, TS-DSP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915332
    NCBI Gene: 68082
  • Gene Overview
    MyGene.info: DUSP19
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:80617214-80631661 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 48.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915332
protein coding gene Chr2:80617045-80632361 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025886
protein coding gene Chr2:81212059-81230530 (+)
A/J MGP_AJ_G0025863
protein coding gene Chr2:78080975-78096239 (+)
AKR/J MGP_AKRJ_G0025832
protein coding gene Chr2:80116342-80131685 (+)
BALB/cJ MGP_BALBcJ_G0025859
protein coding gene Chr2:78209921-78224858 (+)
C3H/HeJ MGP_C3HHeJ_G0025618
protein coding gene Chr2:80358605-80375169 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026305
protein coding gene Chr2:83597631-83613372 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023708
protein coding gene Chr2:75288340-75302704 (+)
CAST/EiJ MGP_CASTEiJ_G0025080
protein coding gene Chr2:80795799-80814074 (+)
CBA/J MGP_CBAJ_G0025599
protein coding gene Chr2:86638294-86657721 (+)
DBA/2J MGP_DBA2J_G0025730
protein coding gene Chr2:77622664-77639312 (+)
FVB/NJ MGP_FVBNJ_G0025692
protein coding gene Chr2:76968294-76983891 (+)
LP/J MGP_LPJ_G0025818
protein coding gene Chr2:81069849-81087201 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025723
protein coding gene Chr2:88516088-88531324 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026361
protein coding gene Chr2:80283794-80298652 (+)
PWK/PhJ MGP_PWKPhJ_G0024823
protein coding gene Chr2:77568936-77583819 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024629
protein coding gene Chr2:80536653-80552427 (+)
WSB/EiJ MGP_WSBEiJ_G0025149
protein coding gene Chr2:80938936-80953732 (+)



Homology
more
  • Human Ortholog
    DUSP19, dual specificity phosphatase 19
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DUSP19, dual specificity phosphatase 19
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DUSP17, LMWDSP3, SKRP1, TS-DSP1
  • Links
    NCBI Gene ID: 142679
    neXtProt AC: NX_Q8WTR2
    UniProt: Q8WTR2

  • Chr Location
    2q32.1; chr2:183078559-183100008 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41565
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DUSP19
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68082 NCBI Gene Model | MGI Sequence Detail 14448 C57BL/6J ±  kb
transcript NM_024438 RefSeq | MGI Sequence Detail 1463 C57BL/6  
polypeptide Q8K4T5 UniProt | EBI | MGI Sequence Detail 220 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • EC
  • InterPro Domains
    IPR020417 Atypical dual specificity phosphatase
    IPR024950 Dual specificity phosphatase
    IPR000340 Dual specificity phosphatase, catalytic domain
    IPR020422 Dual specificity protein phosphatase domain
    IPR029021 Protein-tyrosine phosphatase-like
    IPR000387 Tyrosine specific protein phosphatases domain
Molecular
Reagents
less
  • All nucleic 35
    cDNA 35

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139481
References
more
  • Summaries
    All 35
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:227263 Fabre PJ, et al., Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13964-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory