| GO term: | negative regulation of MAPK cascade |
| Synonym: | down regulation of MAPK cascade |
| Synonym: | down-regulation of MAPK cascade |
| Synonym: | downregulation of MAPK cascade |
| Synonym: | down regulation of MAPKKK cascade |
| Synonym: | down-regulation of MAPKKK cascade |
| Synonym: | downregulation of MAPKKK cascade |
| Synonym: | inhibition of MAPK cascade |
| Synonym: | inhibition of MAPKKK cascade |
| Synonym: | negative regulation of MAP kinase cascade |
| Synonym: | negative regulation of MAP kinase kinase kinase cascade |
| Synonym: | negative regulation of MAPKKK cascade |
| Synonym: | negative regulation of mitogen activated protein kinase cascade |
| Synonym: | negative regulation of mitogen-activated protein kinase cascade |
| Synonym: | negative regulation of mitogen activated protein kinase kinase kinase cascade |
| Synonym: | negative regulation of mitogen-activated protein kinase kinase kinase cascade |
| GO id: | GO:0043409 |
| Definition: | Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. |
| Number of paths to term: | 156 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological processnegative regulation of biological processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processnegative regulation of biological processnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processnegative regulation of biological processnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascade +ERK5 cascade +MAPK cascade involved in cell wall biogenesis +MAPK cascade involved in conjugation with cellular fusion +MAPK cascade involved in innate immune response +MAPK cascade involved in osmosensory signaling pathway +MAPK import into nucleus +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of MAPK cascade +stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of signalingnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of signalingregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processbiological regulationregulation of biological processregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processregulation of cell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processregulation of cell communicationregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascade +ERK5 cascade +MAPK cascade involved in cell wall biogenesis +MAPK cascade involved in conjugation with cellular fusion +MAPK cascade involved in innate immune response +MAPK cascade involved in osmosensory signaling pathway +MAPK import into nucleus +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of MAPK cascade +stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processsignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascade +ERK5 cascade +MAPK cascade involved in cell wall biogenesis +MAPK cascade involved in conjugation with cellular fusion +MAPK cascade involved in innate immune response +MAPK cascade involved in osmosensory signaling pathway +MAPK import into nucleus +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of MAPK cascade +stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascade +ERK5 cascade +MAPK cascade involved in cell wall biogenesis +MAPK cascade involved in conjugation with cellular fusion +MAPK cascade involved in innate immune response +MAPK cascade involved in osmosensory signaling pathway +MAPK import into nucleus +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of MAPK cascade +stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processnegative regulation of biological processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processnegative regulation of biological processnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processnegative regulation of biological processnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processnegative regulation of biological processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processnegative regulation of biological processnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processnegative regulation of biological processnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascade +ERK5 cascade +MAPK cascade involved in cell wall biogenesis +MAPK cascade involved in conjugation with cellular fusion +MAPK cascade involved in innate immune response +MAPK cascade involved in osmosensory signaling pathway +MAPK import into nucleus +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of MAPK cascade +stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadeactivation of MAPKK activity +activation of MAPKKK activity +inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +positive regulation of MAPK cascade +regulation of ERK1 and ERK2 cascade +regulation of ERK5 cascade +regulation of MAP kinase activity +regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of response to stimulusnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein kinase B signaling cascadenegative regulation of protein kinase C signaling cascadenegative regulation of septation initiation signaling cascadenegative regulation of stress-activated protein kinase signaling cascade +biological_processregulation of biological processregulation of response to stimulusregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of I-kappaB kinase/NF-kappaB cascade +negative regulation of JAK-STAT cascade +negative regulation of MAPK cascade [GO:0043409] (104 genes, 150 annotations)inactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascadenegative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +negative regulation of protein
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