Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DHRS7B
  • Mouse genes Dhrs7b
  • Rat genes Dhrs7b
  • Zfish genes dhrs7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dhrs7b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Dhrs7b	IPI	UniProtKB:A2A935	Mouse	PMID:28930673
Molecular Function	GO:0005515	protein binding	Dhrs7b	IPI	UniProtKB:P70168	Mouse	PMID:28930673
Molecular Function	GO:0005515	protein binding	Dhrs7b	IPI	UniProtKB:P37238	Mouse	PMID:28930673
Molecular Function	GO:0005515	protein binding	Dhrs7b	IPI	UniProtKB:Q8C0N2	Mouse	PMID:28930673
Molecular Function	GO:0005515	protein binding	Dhrs7b	IPI	UniProtKB:P23204	Mouse	PMID:28930673
Molecular Function	GO:0003714	transcription corepressor activity	Dhrs7b	IMP		Mouse	PMID:28930673
Molecular Function	GO:0003714	transcription corepressor activity	Dhrs7b	IDA		Mouse	PMID:28930673
Cellular Component	GO:0016020	membrane	DHRS7B	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Dhrs7b	IDA		Mouse	PMID:28930673
Cellular Component	GO:0005634	nucleus	Dhrs7b	IDA		Mouse	PMID:28930673
Cellular Component	GO:0005777	peroxisome	Dhrs7b	IDA		Mouse	PMID:28930673
Cellular Component	GO:0005667	transcription regulator complex	Dhrs7b	IPI	UniProtKB:A2A935	Mouse	PMID:28930673
Biological Process	GO:0060612	adipose tissue development	Dhrs7b	IMP	MGI:MGI:2669525,MGI:MGI:5749209	Mouse	PMID:28930673
Biological Process	GO:0050873	brown fat cell differentiation	Dhrs7b	IDA		Mouse	PMID:28930673
Biological Process	GO:0008611	ether lipid biosynthetic process	Dhrs7b	IMP	MGI:MGI:5749209	Mouse	PMID:25565205
Biological Process	GO:0006954	inflammatory response	Dhrs7b	IMP	MGI:MGI:3765070	Mouse	PMID:25565205
Biological Process	GO:0032091	negative regulation of protein binding	Dhrs7b	IDA		Mouse	PMID:28930673
Biological Process	GO:0030223	neutrophil differentiation	Dhrs7b	IMP	MGI:MGI:5749209	Mouse	PMID:25565205
Biological Process	GO:0006656	phosphatidylcholine biosynthetic process	Dhrs7b	IMP		Mouse	PMID:28930673
Biological Process	GO:0120161	regulation of cold-induced thermogenesis	Dhrs7b	IMP	MGI:MGI:2669525,MGI:MGI:5749209	Mouse	PMID:28930673
Biological Process	GO:0006355	regulation of DNA-templated transcription	Dhrs7b	IDA		Mouse	PMID:28930673
Biological Process	GO:0006355	regulation of DNA-templated transcription	Dhrs7b	IMP		Mouse	PMID:28930673
Biological Process	GO:0010468	regulation of gene expression	Dhrs7b	IMP		Mouse	PMID:28930673
Biological Process	GO:0010468	regulation of gene expression	Dhrs7b	IMP	MGI:MGI:2669525,MGI:MGI:5749209	Mouse	PMID:28930673

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern