Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYTH2
  • Mouse genes Cyth2
  • Rat genes Cyth2
  • Zfish genes cyth2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyth2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Cyth2	IDA		Mouse	MGI:MGI:5520046|PMID:18042453
Molecular Function	GO:0070679	inositol 1,4,5 trisphosphate binding	Cyth2	IDA		Mouse	MGI:MGI:5520047|PMID:15359279
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:P84077	Human	PMID:10198630
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:P84077	Human	PMID:14654833
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:P29274	Human	PMID:16027149
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q96HB5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q9Y487	Human	PMID:16415858
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:P40617	Human	PMID:17398095
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:P49703	Human	PMID:17398095
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:P56559	Human	PMID:17398095
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:P84077	Human	PMID:17563369
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:G9CGD6	Human	PMID:22085542
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q6P9H4	Human	PMID:22085542
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q99836-1	Human	PMID:23143332
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q96HB5-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q3KP66	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q96HB5-4	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q8WWN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q969H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH2	IPI	UniProtKB:Q96HB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cyth2	IPI	UniProtKB:P15920	Mouse	MGI:MGI:3694285|PMID:16415858
Molecular Function	GO:0005515	protein binding	Cyth2	IPI	RGD:735159	Rat	PMID:12920129|RGD:1299642
Cellular Component	GO:0005923	bicellular tight junction	Cyth2	IDA		Mouse	MGI:MGI:4420836|PMID:20080746
Cellular Component	GO:0005737	cytoplasm	CYTH2	IDA		Human	PMID:17398095
Cellular Component	GO:0098892	extrinsic component of postsynaptic specialization membrane	Cyth2	IDA		Rat	PMID:11850456|RGD:70394
Cellular Component	GO:0098978	glutamatergic synapse	Cyth2	IDA		Mouse	PMID:30151872
Cellular Component	GO:0005886	plasma membrane	CYTH2	IDA		Human	PMID:17398095
Cellular Component	GO:0098794	postsynapse	Cyth2	IDA		Mouse	PMID:30151872
Cellular Component	GO:0001726	ruffle	Cyth2	IDA		Rat	PMID:12032543|RGD:625544
Biological Process	GO:2000171	negative regulation of dendrite development	Cyth2	IMP		Rat	PMID:12032543|RGD:625544

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern