Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CTNNA2
  • Mouse genes Ctnna2
  • Rat genes Ctnna2
  • Zfish genes ctnna2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ctnna2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	CTNNA2	IDA		Human	PMID:30013181
Molecular Function	GO:0045296	cadherin binding	CTNNA2	HDA		Human	PMID:25468996
Molecular Function	GO:0042802	identical protein binding	Ctnna2	IPI	UniProtKB:Q61301	Mouse	MGI:MGI:5476862|PMID:23417122
Molecular Function	GO:0005515	protein binding	CTNNA2	IPI	UniProtKB:Q9UID6	Human	PMID:16182284
Cellular Component	GO:0005912	adherens junction	Ctnna2	IDA		Mouse	MGI:MGI:3619804|PMID:16457793
Cellular Component	GO:0005912	adherens junction	Ctnna2	IDA		Mouse	PMID:12695331
Cellular Component	GO:0005912	adherens junction	Ctnna2	IDA		Mouse	PMID:15630473
Cellular Component	GO:0005912	adherens junction	Ctnna2	IDA		Mouse	PMID:19129494
Cellular Component	GO:0030424	axon	Ctnna2	IMP		Mouse	MGI:MGI:3654578|PMID:16691566
Cellular Component	GO:0016323	basolateral plasma membrane	Ctnna2	IDA		Mouse	PMID:9950951
Cellular Component	GO:0005737	cytoplasm	CTNNA2	IDA		Human	PMID:16182284
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	Ctnna2	IPI		Mouse	PMID:8909549
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	Ctnna2	IDA		Mouse	PMID:8909549
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	Ctnna2	IPI		Mouse	PMID:8909549
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	Ctnna2	IDA		Mouse	PMID:8909549
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Ctnna2	IPI		Mouse	PMID:8909549
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Ctnna2	IDA		Mouse	PMID:8909549
Cellular Component	GO:0030027	lamellipodium	Ctnna2	IDA		Mouse	PMID:14657280
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Ctnna2	IPI		Mouse	PMID:8909549
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Ctnna2	IDA		Mouse	PMID:8909549
Cellular Component	GO:0014069	postsynaptic density	Ctnna2	IDA		Mouse	PMID:17114649
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Ctnna2	IDA		Mouse	PMID:8909549
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Ctnna2	IDA		Mouse	PMID:8909549
Biological Process	GO:0007409	axonogenesis	Ctnna2	IMP		Mouse	MGI:MGI:3654578|PMID:16691566
Biological Process	GO:0048854	brain morphogenesis	Ctnna2	IMP		Mouse	MGI:MGI:3654578|PMID:16691566
Biological Process	GO:0048854	brain morphogenesis	Ctnna2	IMP		Mouse	MGI:MGI:2181860|PMID:12089526
Biological Process	GO:0048813	dendrite morphogenesis	Ctnna2	IMP		Mouse	MGI:MGI:3621696|PMID:12123610
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	Ctnna2	IMP		Mouse	PMID:15034585
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	Ctnna2	IDA		Mouse	PMID:15034585
Biological Process	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	CTNNA2	IMP		Human	PMID:30013181
Biological Process	GO:0060134	prepulse inhibition	Ctnna2	IMP		Mouse	MGI:MGI:2181860|PMID:12089526
Biological Process	GO:0021942	radial glia guided migration of Purkinje cell	Ctnna2	IMP		Mouse	MGI:MGI:3621696|PMID:12123610
Biological Process	GO:0021942	radial glia guided migration of Purkinje cell	Ctnna2	IMP		Mouse	MGI:MGI:2181860|PMID:12089526
Biological Process	GO:2001222	regulation of neuron migration	CTNNA2	IMP		Human	PMID:30013181
Biological Process	GO:0010975	regulation of neuron projection development	CTNNA2	IMP		Human	PMID:30013181
Biological Process	GO:0051823	regulation of synapse structural plasticity	Ctnna2	IMP		Mouse	MGI:MGI:3628965|PMID:15034585

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern