Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COL3A1
  • Mouse genes Col3a1
  • Rat genes Col3a1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col3a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	COL3A1	IMP		Human	PMID:7487954
Molecular Function	GO:0005201	extracellular matrix structural constituent	COL3A1	IMP		Human	PMID:9036918
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	COL3A1	HDA		Human	PMID:28344315
Molecular Function	GO:0005178	integrin binding	COL3A1	IMP		Human	PMID:9573018
Molecular Function	GO:0048407	platelet-derived growth factor binding	COL3A1	IDA		Human	PMID:8900172
Molecular Function	GO:0002020	protease binding	COL3A1	IPI	UniProtKB:P39900	Human	PMID:19932771
Molecular Function	GO:0005515	protein binding	COL3A1	IPI	UniProtKB:Q6GTX8	Human	PMID:16754721
Molecular Function	GO:0005515	protein binding	COL3A1	IPI	UniProtKB:P04275	Human	PMID:16912226
Molecular Function	GO:0005515	protein binding	COL3A1	IPI	UniProtKB:O01949	Human	PMID:20015075
Molecular Function	GO:0005515	protein binding	COL3A1	IPI	UniProtKB:Q9Y653	Human	PMID:28258187
Molecular Function	GO:0005515	protein binding	COL3A1	IPI	UniProtKB:P04275	Human	PMID:2839553
Molecular Function	GO:0046332	SMAD binding	Col3a1	IPI	PR:O35253	Mouse	PMID:14559231
Molecular Function	GO:0046332	SMAD binding	Col3a1	IPI	PR:P97471	Mouse	PMID:14559231
Molecular Function	GO:0046332	SMAD binding	Col3a1	IPI	PR:Q8BUN5	Mouse	PMID:14559231
Cellular Component	GO:0005581	collagen trimer	Col3a1	IDA		Mouse	PMID:17662583
Cellular Component	GO:0005581	collagen trimer	Col3a1	IDA		Mouse	PMID:8686743
Cellular Component	GO:0005586	collagen type III trimer	COL3A1	IMP		Human	PMID:17576241
Cellular Component	GO:0005586	collagen type III trimer	COL3A1	IDA		Human	PMID:19932771
Cellular Component	GO:0005586	collagen type III trimer	COL3A1	IMP		Human	PMID:7487954
Cellular Component	GO:0005586	collagen type III trimer	Col3a1	IDA		Mouse	PMID:7825727
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL3A1	IMP		Human	PMID:14970208
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL3A1	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL3A1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL3A1	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL3A1	IMP		Human	PMID:7487954
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL3A1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL3A1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col3a1	HDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col3a1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col3a1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col3a1	IDA		Rat	PMID:20610530|RGD:7257557
Cellular Component	GO:0031012	extracellular matrix	Col3a1	IDA		Mouse	PMID:2209468
Cellular Component	GO:0031012	extracellular matrix	Col3a1	IDA		Mouse	PMID:10022501
Cellular Component	GO:0031012	extracellular matrix	Col3a1	IDA		Mouse	PMID:8984825
Cellular Component	GO:0005576	extracellular region	COL3A1	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	COL3A1	IDA		Human	PMID:7487954
Cellular Component	GO:0005615	extracellular space	Col3a1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0035904	aorta development	Col3a1	IMP	MGI:MGI:5306912	Mouse	PMID:21071432
Biological Process	GO:0035904	aorta development	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:20587693
Biological Process	GO:0035904	aorta development	Col3a1	IMP		Mouse	PMID:23630948
Biological Process	GO:0060414	aorta smooth muscle tissue morphogenesis	Col3a1	IMP		Mouse	MGI:MGI:5307011|PMID:21071432
Biological Process	GO:0071711	basement membrane organization	Col3a1	IMP		Mouse	PMID:22235340
Biological Process	GO:0001568	blood vessel development	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:9050868
Biological Process	GO:0051216	cartilage development	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:31655293
Biological Process	GO:0007160	cell-matrix adhesion	COL3A1	IDA		Human	PMID:16912226
Biological Process	GO:0071230	cellular response to amino acid stimulus	Col3a1	IDA		Mouse	PMID:20548288
Biological Process	GO:0021987	cerebral cortex development	Col3a1	IMP		Mouse	MGI:MGI:5288127|PMID:21768377
Biological Process	GO:0002062	chondrocyte differentiation	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:31655293
Biological Process	GO:0030199	collagen fibril organization	COL3A1	IMP		Human	PMID:7546986
Biological Process	GO:0030199	collagen fibril organization	COL3A1	IMP		Human	PMID:9036918
Biological Process	GO:0030199	collagen fibril organization	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:20587693
Biological Process	GO:0030199	collagen fibril organization	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:31655293
Biological Process	GO:0030199	collagen fibril organization	Col3a1	IMP		Mouse	PMID:29551664
Biological Process	GO:0030199	collagen fibril organization	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:24820199
Biological Process	GO:0030199	collagen fibril organization	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:9050868
Biological Process	GO:0048565	digestive tract development	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:20587693
Biological Process	GO:0048565	digestive tract development	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:9050868
Biological Process	GO:0048251	elastic fiber assembly	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:24820199
Biological Process	GO:0060350	endochondral bone morphogenesis	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:17960558
Biological Process	GO:0030198	extracellular matrix organization	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:25330296
Biological Process	GO:0030198	extracellular matrix organization	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:25330296
Biological Process	GO:0030198	extracellular matrix organization	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:31655293
Biological Process	GO:0048144	fibroblast proliferation	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:17960558
Biological Process	GO:0010467	gene expression	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:17960558
Biological Process	GO:0010467	gene expression	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:25330296
Biological Process	GO:0010467	gene expression	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:25330296
Biological Process	GO:0007507	heart development	COL3A1	IMP		Human	PMID:7546986
Biological Process	GO:0001701	in utero embryonic development	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:25330296
Biological Process	GO:0001701	in utero embryonic development	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:25330296
Biological Process	GO:0007229	integrin-mediated signaling pathway	COL3A1	IMP		Human	PMID:14970208
Biological Process	GO:0021819	layer formation in cerebral cortex	Col3a1	IMP		Mouse	PMID:22235340
Biological Process	GO:0036022	limb joint morphogenesis	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:31655293
Biological Process	GO:0030324	lung development	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:17960558
Biological Process	GO:0035264	multicellular organism growth	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:17960558
Biological Process	GO:0050777	negative regulation of immune response	COL3A1	IMP		Human	PMID:16754721
Biological Process	GO:2001223	negative regulation of neuron migration	Col3a1	IMP		Mouse	MGI:MGI:5288127|PMID:21768377
Biological Process	GO:0001764	neuron migration	Col3a1	IMP		Mouse	PMID:22235340
Biological Process	GO:0018149	peptide cross-linking	COL3A1	IDA		Human	PMID:16754721
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	Col3a1	IDA		Mouse	MGI:MGI:5288127|PMID:21768377
Biological Process	GO:1990776	response to angiotensin	Col3a1	IMP		Mouse	PMID:23630948
Biological Process	GO:0034097	response to cytokine	COL3A1	IDA		Human	PMID:16360482
Biological Process	GO:0034097	response to cytokine	COL3A1	IDA		Human	PMID:9076960
Biological Process	GO:0009612	response to mechanical stimulus	Col3a1	IEP		Rat	PMID:20839322|RGD:7257561
Biological Process	GO:0009314	response to radiation	COL3A1	IDA		Human	PMID:14736764
Biological Process	GO:0001501	skeletal system development	Col3a1	IEP		Rat	PMID:10373016|RGD:704391
Biological Process	GO:0043588	skin development	COL3A1	IMP		Human	PMID:9036918
Biological Process	GO:0043588	skin development	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:25330296
Biological Process	GO:0043588	skin development	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:24820199
Biological Process	GO:0043588	skin development	Col3a1	IMP	MGI:MGI:1857431	Mouse	PMID:25330296
Biological Process	GO:0097435	supramolecular fiber organization	COL3A1	IMP		Human	PMID:14970208
Biological Process	GO:0001894	tissue homeostasis	Col3a1	IMP		Mouse	PMID:29551664
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	COL3A1	IDA		Human	PMID:16360482
Biological Process	GO:0032905	transforming growth factor beta1 production	Col3a1	IMP	MGI:MGI:1860700	Mouse	PMID:24820199
Biological Process	GO:0042060	wound healing	COL3A1	IDA		Human	PMID:1466622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern