Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COBL
  • Mouse genes Cobl
  • Rat genes Cobl
  • Zfish genes cobl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cobl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003785	actin monomer binding	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Molecular Function	GO:0005515	protein binding	COBL	IPI	UniProtKB:Q9BY11	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	COBL	IPI	UniProtKB:Q9BY11	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	COBL	IPI	UniProtKB:P13196	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COBL	IPI	UniProtKB:Q9UNF0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cobl	IPI	UniProtKB:Q9Z0W5	Mouse	MGI:MGI:5696660|PMID:26334624
Molecular Function	GO:0005515	protein binding	Cobl	IPI	UniProtKB:Q9Z0W5	Mouse	MGI:MGI:3765263|PMID:17956734
Molecular Function	GO:0005515	protein binding	Cobl	IPI	UniProtKB:Q5I2Z0|UniProtKB:Q9QY17|UniProtKB:Q9Z0W5	Mouse	MGI:MGI:5287916|PMID:21725280
Molecular Function	GO:0005515	protein binding	Cobl	IPI	UniProtKB:Q9Z0W5	Mouse	MGI:MGI:5287916|PMID:21725280
Molecular Function	GO:0005515	protein binding	Cobl	IPI	UniProtKB:Q9Z0W5	Rat	PMID:21725280|RGD:8554579
Molecular Function	GO:0005515	protein binding	Cobl	IPI	UniProtKB:Q9Z0W5	Rat	PMID:26334624|RGD:11068797
Cellular Component	GO:0005884	actin filament	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Cellular Component	GO:0030424	axon	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Cellular Component	GO:0044295	axonal growth cone	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Cellular Component	GO:0005938	cell cortex	Cobl	IDA		Mouse	MGI:MGI:5287916|PMID:21725280
Cellular Component	GO:0005938	cell cortex	Cobl	IDA		Rat	PMID:21725280|RGD:8554579
Cellular Component	GO:0030425	dendrite	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Cellular Component	GO:0044294	dendritic growth cone	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Cellular Component	GO:0016020	membrane	Cobl	IDA		Mouse	MGI:MGI:5287916|PMID:21725280
Cellular Component	GO:0043025	neuronal cell body	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Cobl	IDA		Mouse	MGI:MGI:5287916|PMID:21725280
Cellular Component	GO:0005886	plasma membrane	Cobl	IDA		Rat	PMID:21725280|RGD:8554579
Cellular Component	GO:0001726	ruffle	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Cellular Component	GO:1990357	terminal web	Cobl	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Biological Process	GO:0030036	actin cytoskeleton organization	Cobl	IMP		Mouse	PMID:29891944
Biological Process	GO:0051639	actin filament network formation	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Biological Process	GO:0030041	actin filament polymerization	Cobl	IMP		Mouse	MGI:MGI:3765263|PMID:17956734
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	cobl	IMP	ZFIN:ZDB-MRPHLNO-130522-4	Zfish	PMID:23203810
Biological Process	GO:0060271	cilium assembly	cobl	IMP	ZFIN:ZDB-MRPHLNO-110218-2	Zfish	PMID:21129373
Biological Process	GO:0048669	collateral sprouting in absence of injury	Cobl	IMP		Mouse	MGI:MGI:3765263|PMID:17956734
Biological Process	GO:0048565	digestive tract development	Cobl	IEP		Mouse	MGI:MGI:76306|PMID:7586755
Biological Process	GO:0000578	embryonic axis specification	Cobl	IEP		Mouse	MGI:MGI:76306|PMID:7586755
Biological Process	GO:0033504	floor plate development	Cobl	IEP		Mouse	MGI:MGI:76306|PMID:7586755
Biological Process	GO:0003146	heart jogging	cobl	IMP	ZFIN:ZDB-MRPHLNO-110218-2	Zfish	PMID:21129373
Biological Process	GO:0001947	heart looping	cobl	IMP	ZFIN:ZDB-MRPHLNO-110218-2	Zfish	PMID:21129373
Biological Process	GO:0001889	liver development	Cobl	IEP		Mouse	MGI:MGI:76306|PMID:7586755
Biological Process	GO:0001843	neural tube closure	Cobl	IGI	MGI:MGI:2135272	Mouse	PMID:14512015
Biological Process	GO:0030903	notochord development	Cobl	IEP		Mouse	MGI:MGI:76306|PMID:7586755
Biological Process	GO:1900006	positive regulation of dendrite development	Cobl	IDA		Mouse	MGI:MGI:5287916|PMID:21725280
Biological Process	GO:1900029	positive regulation of ruffle assembly	Cobl	IDA		Mouse	MGI:MGI:3765263|PMID:17956734
Biological Process	GO:0001757	somite specification	Cobl	IEP		Mouse	MGI:MGI:76306|PMID:7586755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern