Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHRNG
  • Mouse genes Chrng
  • Rat genes Chrng
  • Zfish genes chrng
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chrng

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015464	acetylcholine receptor activity	chrng	IDA		Zfish	PMID:22580045
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrng	IGI	MGI:MGI:87890	Mouse	PMID:8798466
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrng	IGI	MGI:MGI:87885	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrng	IGI	MGI:MGI:87893	Mouse	PMID:8798466
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrng	IGI	MGI:MGI:87890	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrng	IGI	MGI:MGI:87893	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrng	IDA		Rat	PMID:1702709|RGD:68734
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrng	IDA		Rat	PMID:22461452|RGD:8549758
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	Chrng	IDA		Rat	PMID:1702709|RGD:68734
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:P60411	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:P60409	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:P60410	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:P60411	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:Q15323	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:Q7Z3S9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CHRNG	IPI	UniProtKB:Q7Z3S9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Chrng	IPI	PR:P09690	Mouse	PMID:8798466
Molecular Function	GO:0005515	protein binding	Chrng	IPI	PR:P35564	Mouse	PMID:8798466
Molecular Function	GO:0005515	protein binding	Chrng	IPI	PR:P02716	Mouse	PMID:8798466
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrng	IDA		Mouse	PMID:8798466
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrng	IDA		Rat	PMID:22461452|RGD:8549758
Cellular Component	GO:0005892	acetylcholine-gated channel complex	chrng	IDA		Zfish	PMID:22580045
Cellular Component	GO:0005886	plasma membrane	Chrng	IDA		Mouse	PMID:12388596
Cellular Component	GO:0045211	postsynaptic membrane	Chrng	IDA		Mouse	PMID:15883046
Cellular Component	GO:0045202	synapse	chrng	IDA		Zfish	PMID:21844221|ZFIN:ZDB-PUB-110817-5
Biological Process	GO:1905145	cellular response to acetylcholine	chrng	IGI	ZFIN:ZDB-GENO-210810-10	Zfish	PMID:32284992
Biological Process	GO:0007268	chemical synaptic transmission	Chrng	IGI	MGI:MGI:87890	Mouse	MGI:MGI:82783|PMID:8798466
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Chrng	IGI	MGI:MGI:87890	Mouse	MGI:MGI:82783|PMID:8798466
Biological Process	GO:0060079	excitatory postsynaptic potential	Chrng	IGI	MGI:MGI:87890	Mouse	MGI:MGI:82783|PMID:8798466
Biological Process	GO:0098655	monoatomic cation transmembrane transport	Chrng	IGI	MGI:MGI:87890	Mouse	MGI:MGI:82783|PMID:8798466
Biological Process	GO:0006812	monoatomic cation transport	Chrng	IDA		Rat	PMID:22461452|RGD:8549758
Biological Process	GO:0042391	regulation of membrane potential	Chrng	IGI	MGI:MGI:87893	Mouse	PMID:8798466
Biological Process	GO:0042391	regulation of membrane potential	Chrng	IGI	MGI:MGI:87893	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrng	IGI	MGI:MGI:87890	Mouse	PMID:8798466
Biological Process	GO:0042391	regulation of membrane potential	Chrng	IGI	MGI:MGI:87885	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrng	IGI	MGI:MGI:87890	Mouse	PMID:2383398
Biological Process	GO:0003009	skeletal muscle contraction	Chrng	IDA		Rat	PMID:22461452|RGD:8549758
Biological Process	GO:0007271	synaptic transmission, cholinergic	chrng	IDA		Zfish	PMID:21844221

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern