Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHD2
  • Mouse genes Chd2
  • Rat genes Chd2
  • Zfish genes chd2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042393	histone binding	Chd2	IDA		Mouse	MGI:MGI:5532896|PMID:22569126
Molecular Function	GO:0005515	protein binding	CHD2	IPI	UniProtKB:Q8WV44	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CHD2	IPI	UniProtKB:Q8N7W2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHD2	IPI	UniProtKB:Q8WV44	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHD2	IPI	UniProtKB:Q969V4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHD2	IPI	UniProtKB:Q9NVV9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHD2	IPI	UniProtKB:Q9UJV3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Chd2	IPI	UniProtKB:P10085	Mouse	MGI:MGI:5532896|PMID:22569126
Molecular Function	GO:0003723	RNA binding	CHD2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	CHD2	HDA		Human	PMID:22681889
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Chd2	IMP		Mouse	MGI:MGI:5532896|PMID:22569126
Cellular Component	GO:0005634	nucleus	Chd2	IDA		Mouse	MGI:MGI:5532896|PMID:22569126
Biological Process	GO:0043009	chordate embryonic development	chd2	IMP	ZFIN:ZDB-MRPHLNO-140320-1	Zfish	PMID:24207121
Biological Process	GO:0006974	DNA damage response	Chd2	IMP	MGI:MGI:3800602	Mouse	PMID:19137022
Biological Process	GO:0010467	gene expression	Chd2	IMP		Mouse	PMID:27783602
Biological Process	GO:0060218	hematopoietic stem cell differentiation	Chd2	IMP	MGI:MGI:3800602	Mouse	PMID:19137022
Biological Process	GO:0040011	locomotion	chd2	IMP	ZFIN:ZDB-MRPHLNO-140320-1	Zfish	PMID:24207121
Biological Process	GO:0007517	muscle organ development	Chd2	IMP		Mouse	MGI:MGI:5532896|PMID:22569126

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern