Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBFB
  • Mouse genes Cbfb
  • Rat genes Cbfb
  • Zfish genes cbfb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbfb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Cbfb	IDA		Rat	PMID:9930766|RGD:634635
Molecular Function	GO:0003677	DNA binding	cbfb	IPI	UniProtKB:Q01196	Zfish	PMID:11110689
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q01196-1	Human	PMID:10856244
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q01196-1	Human	PMID:12217689
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q01196	Human	PMID:17431401
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:P11137	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q9NVM9	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:P12504	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:P12504	Human	PMID:24402281
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q01196	Human	PMID:25678665
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q01196	Human	PMID:2845103
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q01196-8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q13761-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBFB	IPI	UniProtKB:Q01196	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	Cbfb	IPI	UniProtKB:Q9JI13	Mouse	MGI:MGI:2136064|PMID:11404095
Molecular Function	GO:0046982	protein heterodimerization activity	cbfb	IPI	UniProtKB:Q01196	Zfish	PMID:11110689
Molecular Function	GO:0043565	sequence-specific DNA binding	Cbfb	IDA		Mouse	MGI:MGI:3772948|PMID:18258917
Molecular Function	GO:0003712	transcription coregulator activity	cbfb	IDA		Zfish	PMID:25575784
Cellular Component	GO:0016513	core-binding factor complex	cbfb	IPI	UniProtKB:Q01196	Zfish	PMID:11110689
Cellular Component	GO:0016020	membrane	CBFB	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	Cbfb	IDA		Mouse	PMID:12434156
Cellular Component	GO:0005634	nucleus	cbfb	IDA		Zfish	PMID:20605922
Cellular Component	GO:0030018	Z disc	cbfb	IDA		Zfish	PMID:20605922
Biological Process	GO:0048469	cell maturation	Cbfb	IMP	MGI:MGI:2447293	Mouse	PMID:12434156
Biological Process	GO:0060216	definitive hemopoiesis	Cbfb	IMP	MGI:MGI:1933624	Mouse	PMID:9159135
Biological Process	GO:0060047	heart contraction	cbfb	IMP	ZFIN:ZDB-MRPHLNO-101021-5	Zfish	PMID:20605922
Biological Process	GO:0030097	hemopoiesis	cbfb	IMP	ZFIN:ZDB-GENO-130531-3	Zfish	PMID:24850758
Biological Process	GO:0030098	lymphocyte differentiation	Cbfb	IMP	MGI:MGI:1934195	Mouse	PMID:12434155
Biological Process	GO:0097535	lymphoid lineage cell migration into thymus	cbfb	IMP	ZFIN:ZDB-MRPHLNO-180921-2	Zfish	PMID:29343500
Biological Process	GO:0030099	myeloid cell differentiation	Cbfb	IMP	MGI:MGI:1934195	Mouse	PMID:12434155
Biological Process	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	Cbfb	IMP		Mouse	MGI:MGI:3772948|PMID:18258917
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbfb	IMP		Mouse	MGI:MGI:3772948|PMID:18258917
Biological Process	GO:0001503	ossification	Cbfb	IMP	MGI:MGI:2447293	Mouse	PMID:12434156
Biological Process	GO:0001503	ossification	Cbfb	IMP	MGI:MGI:1934195	Mouse	PMID:12434155
Biological Process	GO:0001649	osteoblast differentiation	Cbfb	IMP	MGI:MGI:2447293	Mouse	PMID:12434156
Biological Process	GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	Cbfb	IMP		Mouse	MGI:MGI:3772948|PMID:18258917
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Cbfb	IDA		Mouse	PMID:12434156
Biological Process	GO:0000209	protein polyubiquitination	CBFB	IMP		Human	PMID:22190036
Biological Process	GO:0045214	sarcomere organization	cbfb	IMP	ZFIN:ZDB-MRPHLNO-101021-5	Zfish	PMID:20605922
Biological Process	GO:0048769	sarcomerogenesis	cbfb	IMP	ZFIN:ZDB-MRPHLNO-101021-5	Zfish	PMID:20605922

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern