Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cacng2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CACNG2
- Mouse genes Cacng2
- Rat genes Cacng2
- Zfish genes cacng2a,cacng2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacng2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Cacng2	IPI	RGD:621531	Rat	PMID:17194442\|RGD:2304049
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Cacng2	IPI	RGD:621531	Rat	PMID:19942860\|RGD:4107483
Molecular Function	GO:0005515	protein binding	CACNG2	IPI	UniProtKB:P42261	Human	PMID:20805473
Molecular Function	GO:0005515	protein binding	CACNG2	IPI	UniProtKB:O43516-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P23818	Mouse	MGI:MGI:4833731\|PMID:20805473
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P31016	Rat	PMID:12359873\|RGD:8553390
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P19490	Rat	PMID:19208802\|RGD:13432301
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P19490	Rat	PMID:19805317\|RGD:13432333
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P19490	Rat	PMID:20805473\|RGD:8553646
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P19490	Rat	PMID:21376300\|RGD:10412303
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P19491	Rat	PMID:21376300\|RGD:10412303
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P19490	Rat	PMID:24418105\|RGD:8553314
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P19491	Rat	PMID:24418105\|RGD:8553314
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:P31016	Rat	PMID:24418105\|RGD:8553314
Molecular Function	GO:0005515	protein binding	Cacng2	IPI	UniProtKB:D3ZAA9,UniProtKB:P19491,UniProtKB:P31016	Rat	PMID:27756895\|RGD:12790644
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacng2	IMP	MGI:MGI:1856548	Mouse	PMID:12151514
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Cacng2	IDA		Mouse	PMID:22632720
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Cacng2	IDA		Rat	PMID:19265014\|RGD:8554136
Cellular Component	GO:0009986	cell surface	Cacng2	IDA		Rat	PMID:21276808\|RGD:13524552
Cellular Component	GO:0044300	cerebellar mossy fiber	Cacng2	IDA		Rat	PMID:23751177\|RGD:13524561
Cellular Component	GO:0005829	cytosol	Cacng2	IDA		Rat	PMID:21220022\|RGD:13515069
Cellular Component	GO:0098978	glutamatergic synapse	Cacng2	IDA		Mouse	PMID:11140673
Cellular Component	GO:0098978	glutamatergic synapse	Cacng2	IMP		Mouse	PMID:11140673
Cellular Component	GO:0098978	glutamatergic synapse	Cacng2	IEP		Mouse	PMID:11140673
Cellular Component	GO:0098978	glutamatergic synapse	Cacng2	IPI		Mouse	PMID:11140673
Cellular Component	GO:0098978	glutamatergic synapse	Cacng2	IDA		Mouse	PMID:17329211
Cellular Component	GO:0098978	glutamatergic synapse	Cacng2	IMP		Mouse	PMID:17329211
Cellular Component	GO:0098978	glutamatergic synapse	Cacng2	IDA		Mouse	PMID:18753375
Cellular Component	GO:0098978	glutamatergic synapse	Cacng2	IMP		Mouse	PMID:18753375
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Cacng2	IDA		Mouse	PMID:11140673
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Cacng2	IMP		Mouse	PMID:11140673
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Cacng2	IPI		Mouse	PMID:11140673
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Cacng2	IEP		Mouse	PMID:11140673
Cellular Component	GO:0005886	plasma membrane	Cacng2	IDA		Rat	PMID:21220022\|RGD:13515069
Cellular Component	GO:0014069	postsynaptic density	Cacng2	IDA		Rat	PMID:12771129\|RGD:13515082
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng2	IDA		Mouse	PMID:27076426
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng2	IDA		Rat	PMID:16516319\|RGD:12859073
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng2	IDA		Rat	PMID:21276808\|RGD:13524552
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cacng2	IDA		Mouse	PMID:27076426
Cellular Component	GO:0036477	somatodendritic compartment	Cacng2	IDA		Mouse	MGI:MGI:3794899\|PMID:18341993
Biological Process	GO:0098990	AMPA selective glutamate receptor signaling pathway	cacng2a	IMP	ZFIN:ZDB-MRPHLNO-160526-17	Zfish	PMID:26178704
Biological Process	GO:0060082	eye blink reflex	Cacng2	IEP		Rat	PMID:21319893\|RGD:13515073
Biological Process	GO:0051899	membrane depolarization	Cacng2	IMP	MGI:MGI:1856548	Mouse	PMID:9065835
Biological Process	GO:0060081	membrane hyperpolarization	Cacng2	IMP	MGI:MGI:1856548	Mouse	PMID:9065835
Biological Process	GO:0050877	nervous system process	Cacng2	IMP	MGI:MGI:1856548	Mouse	PMID:9293489
Biological Process	GO:0007528	neuromuscular junction development	Cacng2	IMP	MGI:MGI:1856548	Mouse	PMID:17320843
Biological Process	GO:0099590	neurotransmitter receptor internalization	Cacng2	IMP		Mouse	MGI:MGI:5819335\|PMID:24217640
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Cacng2	IMP		Mouse	PMID:18753375
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Cacng2	IDA		Mouse	PMID:18753375
Biological Process	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome	Cacng2	IMP		Mouse	MGI:MGI:5819335\|PMID:24217640
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	Cacng2	IDA		Rat	PMID:16093395\|RGD:13515081
Biological Process	GO:1904510	positive regulation of protein localization to basolateral plasma membrane	Cacng2	IDA		Rat	PMID:17986442\|RGD:13515070
Biological Process	GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping	Cacng2	IDA		Mouse	PMID:17329211
Biological Process	GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping	Cacng2	IMP		Mouse	PMID:17329211
Biological Process	GO:0006612	protein targeting to membrane	Cacng2	IDA		Rat	PMID:17986442\|RGD:13515070
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng2	IDA		Mouse	MGI:MGI:5887196\|PMID:15758178
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng2	IDA		Rat	PMID:17880894\|RGD:8553817
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng2	IDA		Rat	PMID:18817736\|RGD:8554789
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng2	IDA		Rat	PMID:19234459\|RGD:8554069
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng2	IDA		Rat	PMID:19265014\|RGD:8554136
Biological Process	GO:0042391	regulation of membrane potential	Cacng2	IMP	MGI:MGI:1856548	Mouse	PMID:12151514
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Cacng2	IDA		Mouse	PMID:11140673
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Cacng2	IEP		Mouse	PMID:11140673
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Cacng2	IPI		Mouse	PMID:11140673
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Cacng2	IMP		Mouse	PMID:11140673
Biological Process	GO:0051592	response to calcium ion	Cacng2	IEP		Rat	PMID:21256931\|RGD:13515072
Biological Process	GO:0019226	transmission of nerve impulse	Cacng2	IGI	MGI:MGI:1859167	Mouse	PMID:15677329

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.