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Cacng2
Gene Detail
Symbol

Name
ID
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
MGI:1316660
Synonyms
B230105C07Rik, B930041E13Rik, stargazin, TARP gamma 2
Feature Type
protein coding gene
Genetic Map
Chromosome 15
36.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
Chr15:77991748-78120028 bp, - strand
From VEGA annotation of GRCm38

  128281 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4432  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CACNG2
Gene Tree: Cacng2

Human
homologs
CACNG2, calcium channel, voltage-dependent, gamma subunit 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10369
neXtProt AC: NX_Q9Y698

Human Synonyms: MRD10

Human Chr (Location): 22q13.1; chr22:36560869-36702645 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CACNG2

Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Gene trapped(19) Radiation induced(1) Spontaneous(3) Targeted(5)
Genomic Mutations involving Cacng2 (1)
 
Homozygotes for mutant alleles show growth retardation, movement anomalies including ataxic gait, tremor and head tossing, and neocortical spike-wave seizures.
 
Phenotype Images(5)
Interactions
Cacng2 interacts with 267 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (34)    Tissues (25)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
RT-PCR 10
cDNA source data(20)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cacng2 ; ZFIN cacng2a    NEW 
Molecular
reagents
All nucleic(26) Genomic(4) cDNA(20) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000016425 (Evidence)
Ensembl Gene Model ENSMUSG00000019146 (Evidence)
Entrez Gene 12300 (Evidence)
NIA Mouse Gene Index U197635, U036376
PDB 3JXT
Consensus CDS Project CCDS27608.1
International Mouse Phenotyping Consortium Status Cacng2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016425 VEGA Gene Model | MGI Sequence Detail 128281 C57BL/6J ±  kb
transcript OTTMUST00000039555 VEGA | MGI Sequence Detail 5510 Not Applicable 
polypeptide OTTMUSP00000017670 VEGA | MGI Sequence Detail 323 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(4) UniProt(3)
Polymorphisms
RFLP(2) : SNPs within 2kb(663 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004031 PMP-22/EMP/MP20/Claudin
InterPro IPR005422 Voltage-dependent calcium channel, gamma-2 subunit
InterPro IPR008368 Voltage-dependent calcium channel, gamma subunit
Protein Ontology PR:000004951 voltage-dependent calcium channel gamma-2 subunit
References
(Earliest) J:11008 Noebels JL, et al., Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures [published erratum appears in Epilepsy Res 1992 Mar;11(1):72]. Epilepsy Res. 1990 Nov;7(2):129-35
(Latest) J:211786 Louros SR, et al., A role for stargazin in experience-dependent plasticity. Cell Rep. 2014 Jun 12;7(5):1614-25
All references(111)
Other
accession IDs
MGD-MRK-14624, MGD-MRK-15425, MGI:1925228, MGI:2146187, MGI:98432

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory