Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCOR,BCORP1
  • Mouse genes Bcor
  • Rat genes Bcor
  • Zfish genes bcor
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcor

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	BCOR	IPI	UniProtKB:P41182	Human	PMID:10898795
Molecular Function	GO:0031072	heat shock protein binding	BCOR	IDA		Human	PMID:16943429
Molecular Function	GO:0042826	histone deacetylase binding	BCOR	IPI	UniProtKB:O15379	Human	PMID:10898795
Molecular Function	GO:0042826	histone deacetylase binding	BCOR	IPI	UniProtKB:Q13547	Human	PMID:10898795
Molecular Function	GO:0042826	histone deacetylase binding	BCOR	IPI	UniProtKB:Q9UQL6	Human	PMID:10898795
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q93009	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:P63208	Human	PMID:16943429
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q06587	Human	PMID:16943429
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q8NHM5	Human	PMID:16943429
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q99496	Human	PMID:16943429
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q9BSM1	Human	PMID:16943429
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q8NHM5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q8NHM5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q93009	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q9BSM1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q9BSM1	Human	PMID:26687479
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q8NHM5	Human	PMID:27505670
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q9BSM1	Human	PMID:27505670
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q9HC52	Human	PMID:27505670
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q9BSM1	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BCOR	IPI	UniProtKB:Q9HC52	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	Bcor	IPI	UniProtKB:Q96A23	Mouse	MGI:MGI:5294308|PMID:12522145
Molecular Function	GO:0005515	protein binding	Bcor	IPI	UniProtKB:P41183	Mouse	MGI:MGI:5615321|PMID:25490446
Molecular Function	GO:0005515	protein binding	Bcor	IPI	PR:P23611	Mouse	PMID:25331958
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Bcor	IDA		Mouse	PMID:25331958
Molecular Function	GO:0000976	transcription cis-regulatory region binding	BCOR	IMP		Human	PMID:19578371
Molecular Function	GO:0003714	transcription corepressor activity	BCOR	IDA		Human	PMID:10898795
Molecular Function	GO:0003714	transcription corepressor activity	BCOR	IMP		Human	PMID:15878880
Molecular Function	GO:0003714	transcription corepressor activity	Bcor	IPI	PR:P41183	Mouse	PMID:12776190
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BCOR	IDA		Human	PMID:16943429
Cellular Component	GO:0140261	BCOR complex	BCOR	IDA		Human	PMID:16943429
Cellular Component	GO:0005654	nucleoplasm	BCOR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	BCOR	IDA		Human	PMID:10898795
Cellular Component	GO:0005634	nucleus	BCOR	IDA		Human	PMID:25331958
Cellular Component	GO:0005634	nucleus	Bcor	IDA		Mouse	PMID:12776190
Biological Process	GO:0001835	blastocyst hatching	Bcor	IMP		Mouse	PMID:27869233
Biological Process	GO:0043010	camera-type eye development	bcor	IMP		Zfish	PMID:15004558
Biological Process	GO:0006338	chromatin remodeling	BCOR	IDA		Human	PMID:16943429
Biological Process	GO:0007507	heart development	BCOR	IMP		Human	PMID:17517692
Biological Process	GO:0030502	negative regulation of bone mineralization	BCOR	IMP		Human	PMID:19578371
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BCOR	IDA		Human	PMID:10898795
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BCOR	IMP		Human	PMID:15878880
Biological Process	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	bcor	IMP	ZFIN:ZDB-MRPHLNO-130911-9	Zfish	PMID:23669349
Biological Process	GO:0070171	negative regulation of tooth mineralization	BCOR	IMP		Human	PMID:19578371
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	BCOR	IMP		Human	PMID:19578371
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bcor	IDA		Mouse	PMID:12776190
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bcor	IGI	MGI:MGI:96395	Mouse	PMID:25331958
Biological Process	GO:0021915	neural tube development	bcor	IMP		Zfish	PMID:15004558
Biological Process	GO:0042476	odontogenesis	BCOR	IMP		Human	PMID:17517692
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	bcor	IGI	ZFIN:ZDB-MRPHLNO-120606-5,ZFIN:ZDB-MRPHLNO-130911-9	Zfish	PMID:23669349
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	bcor	IMP	ZFIN:ZDB-MRPHLNO-130911-9	Zfish	PMID:23669349
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	bcor	IGI	ZFIN:ZDB-MRPHLNO-130911-7,ZFIN:ZDB-MRPHLNO-130911-9	Zfish	PMID:23669349
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	bcor	IGI	ZFIN:ZDB-GENO-070209-122,ZFIN:ZDB-MRPHLNO-130911-9	Zfish	PMID:23669349
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	bcor	IGI	ZFIN:ZDB-GENE-020419-32,ZFIN:ZDB-MRPHLNO-130911-9	Zfish	PMID:23669349
Biological Process	GO:0060021	roof of mouth development	BCOR	IMP		Human	PMID:17517692
Biological Process	GO:0065001	specification of axis polarity	BCOR	IMP		Human	PMID:17517692

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern