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Bcor
Gene Detail
 Symbol
Name
ID
Bcor
BCL6 interacting corepressor
MGI:1918708
Synonyms 5830466J11Rik, 8430401K06Rik, D930024N20Rik, mKIAA1575
Feature Type protein coding gene
Genetic Map
Chromosome X
6.83 cM, cytoband A1.2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:12036740-12160355 bp, - strand
From VEGA annotation of GRCm38

  123616 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9809  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Bcor

Human
homologs
Human Homolog BCOR, BCL6 corepressor
NCBI Gene ID 54880
neXtProt AC  NX_Q6W2J9
Human Synonyms  ANOP2, MAA2, MCOPS2
Human Chr (Location)  Xp11.4; chrX:40051246-40177390 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human BCOR
Mutations,
alleles, and
phenotypes
All mutations/alleles(31) : Gene trapped(26) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Male chimeras hemizygous for either of two different gene trapped alleles die by E9.5 exhibiting anomalies in somite formation and heart looping, forebrain fusion, and microcephaly. Hemizygosity for other gene trapped alleles can cause patterning and embryo turning defects or abnormal gastrulation.
 
Phenotype Images(24)
Interactions
Bcor interacts with 270 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process chromatin modification, heart development, ...
Component nucleus, PcG protein complex
Function heat shock protein binding, histone deacetylase binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (242)    Tissues (101)    Images (53)
Theiler Stages: 11, 13, 14, 15, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 150
Northern blot 4
RT-PCR 88
cDNA source data(106)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(112) cDNA(107) Primer pair(5)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000016940 (Evidence)
Ensembl Gene ModelENSMUSG00000040363 (Evidence)
Entrez Gene71458 (Evidence)
UniGene196328
DFCITC1576378, TC1590514, TC1592974
DoTSDT.101737539, DT.103566839, DT.60103667, DT.99854034, DT.99854036
NIA Mouse Gene IndexU039264
Consensus CDS ProjectCCDS30021.1, CCDS30022.1, CCDS40872.1, CCDS40873.1
International Mouse Knockout Project StatusBcor
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016940 VEGA Gene Model | MGI Sequence Detail 123616 C57BL/6J ±  kb
transcript OTTMUST00000041082 VEGA | MGI Sequence Detail 6941 Not Applicable 
polypeptide OTTMUSP00000018407 VEGA | MGI Sequence Detail 1759 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(10) UniProt(4)
Polymorphisms SNPs within 2kb(177 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
Protein Ontology PR:000004709 BCL-6 corepressor
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)
Other
accession IDs
MGI:1923325, MGI:2444213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory