Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATG4B
  • Mouse genes Atg4b
  • Rat genes Atg4b
  • Zfish genes atg4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atg4b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019786	Atg8-specific peptidase activity	ATG4B	IDA		Human	PMID:31315929
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4B	IDA		Human	PMID:15169837
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4B	IDA		Human	PMID:20818167
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4B	IDA		Human	PMID:21177865
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4B	IDA		Human	PMID:26378241
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4B	IDA		Human	PMID:27527864
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4B	IDA		Human	PMID:28821708
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4B	IDA		Human	PMID:29458288
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4B	IDA		Human	PMID:30661429
Molecular Function	GO:0008234	cysteine-type peptidase activity	Atg4b	IDA		Mouse	MGI:MGI:6762552|PMID:29458288
Molecular Function	GO:0004175	endopeptidase activity	ATG4B	IDA		Human	PMID:18387192
Molecular Function	GO:0008233	peptidase activity	Atg4b	IDA		Mouse	MGI:MGI:2684000|PMID:14530254
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9GZQ8	Human	PMID:15187094
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:O95166	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:P60520	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9GZQ8	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9GZQ8	Human	PMID:18083104
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9GZQ8	Human	PMID:19322194
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9GZQ8	Human	PMID:20010802
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:O95166	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:P60520	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9BXW4	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9GZQ8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9H0R8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9H492	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:P60520	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9GZQ8	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:O95166	Human	PMID:25126726
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:A0A0H3LAC5	Human	PMID:30118682
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:P60520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9BXW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9GZQ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9H0R8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG4B	IPI	UniProtKB:Q9H492	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Atg4b	IPI	UniProtKB:Q91Z40	Mouse	MGI:MGI:5007562|PMID:21551061
Molecular Function	GO:0005515	protein binding	Atg4b	IPI	UniProtKB:Q91VR7	Mouse	MGI:MGI:2684000|PMID:14530254
Molecular Function	GO:0005515	protein binding	Atg4b	IPI	PR:O35445	Mouse	PMID:23093945
Molecular Function	GO:0097110	scaffold protein binding	ATG4B	IPI	UniProtKB:Q8NDB2	Human	PMID:23555801
Cellular Component	GO:0005737	cytoplasm	Atg4b	IDA		Mouse	MGI:MGI:2684000|PMID:14530254
Biological Process	GO:0000045	autophagosome assembly	Atg4b	IMP		Mouse	MGI:MGI:5630037|PMID:25578879
Biological Process	GO:0006914	autophagy	ATG4B	IDA		Human	PMID:18387192
Biological Process	GO:0006914	autophagy	ATG4B	IDA		Human	PMID:26378241
Biological Process	GO:0006914	autophagy	ATG4B	IDA		Human	PMID:27527864
Biological Process	GO:0006914	autophagy	ATG4B	IDA		Human	PMID:28821708
Biological Process	GO:0006914	autophagy	Atg4b	IMP		Mouse	MGI:MGI:4829568|PMID:20577052
Biological Process	GO:0009267	cellular response to starvation	Atg4b	IMP		Mouse	MGI:MGI:5630037|PMID:25578879
Biological Process	GO:0016237	lysosomal microautophagy	ATG4B	IDA		Human	PMID:33909989
Biological Process	GO:0000423	mitophagy	ATG4B	IMP		Human	PMID:33773106
Biological Process	GO:0031173	otolith mineralization completed early in development	Atg4b	IMP		Mouse	MGI:MGI:4829568|PMID:20577052
Biological Process	GO:0045732	positive regulation of protein catabolic process	Atg4b	IMP		Rat	PMID:16874114|RGD:2301238
Biological Process	GO:0051697	protein delipidation	ATG4B	IDA		Human	PMID:25327288
Biological Process	GO:0051697	protein delipidation	ATG4B	IDA		Human	PMID:26378241
Biological Process	GO:0051697	protein delipidation	ATG4B	IDA		Human	PMID:28821708
Biological Process	GO:0051697	protein delipidation	ATG4B	IDA		Human	PMID:29458288
Biological Process	GO:0051697	protein delipidation	ATG4B	IDA		Human	PMID:33909989
Biological Process	GO:0051697	protein delipidation	Atg4b	IDA		Mouse	MGI:MGI:6762552|PMID:29458288
Biological Process	GO:0034497	protein localization to phagophore assembly site	ATG4B	IMP		Human	PMID:33773106
Biological Process	GO:0006508	proteolysis	ATG4B	IDA		Human	PMID:15169837
Biological Process	GO:0006508	proteolysis	ATG4B	IDA		Human	PMID:18387192
Biological Process	GO:0006508	proteolysis	ATG4B	IDA		Human	PMID:21177865
Biological Process	GO:0061912	selective autophagy	ATG4B	IEP		Human	PMID:28287329

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern