Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOM
  • Mouse genes Apom
  • Rat genes Apom
  • Zfish genes apom
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apom

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016209	antioxidant activity	APOM	IDA		Human	PMID:22204862
Molecular Function	GO:0016209	antioxidant activity	Apom	IDA		Mouse	MGI:MGI:5427066|PMID:22204862
Molecular Function	GO:0005319	lipid transporter activity	APOM	IDA		Human	PMID:16682745
Molecular Function	GO:0005543	phospholipid binding	APOM	IDA		Human	PMID:22204862
Molecular Function	GO:0005515	protein binding	Apom	IPI	UniProtKB:A2ARV4	Mouse	MGI:MGI:3611102|PMID:16099815
Cellular Component	GO:0034365	discoidal high-density lipoprotein particle	APOM	IDA		Human	PMID:15793583
Cellular Component	GO:0034365	discoidal high-density lipoprotein particle	Apom	IDA		Mouse	MGI:MGI:3575626|PMID:15793583
Cellular Component	GO:0005576	extracellular region	Apom	IDA		Mouse	PMID:15793583
Cellular Component	GO:0005615	extracellular space	Apom	IDA		Rat	PMID:17556016|RGD:2313117
Cellular Component	GO:0034364	high-density lipoprotein particle	APOM	IDA		Human	PMID:22204862
Cellular Component	GO:0034364	high-density lipoprotein particle	Apom	IDA		Mouse	MGI:MGI:5427066|PMID:22204862
Cellular Component	GO:0034362	low-density lipoprotein particle	APOM	IDA		Human	PMID:16682745
Cellular Component	GO:0034366	spherical high-density lipoprotein particle	APOM	IDA		Human	PMID:16682745
Cellular Component	GO:0034361	very-low-density lipoprotein particle	APOM	IDA		Human	PMID:17154273
Biological Process	GO:0033344	cholesterol efflux	APOM	IMP		Human	PMID:15793583
Biological Process	GO:0033344	cholesterol efflux	APOM	IDA		Human	PMID:16682745
Biological Process	GO:0033344	cholesterol efflux	Apom	IMP		Mouse	MGI:MGI:3575626|PMID:15793583
Biological Process	GO:0034380	high-density lipoprotein particle assembly	Apom	IMP		Mouse	MGI:MGI:3575626|PMID:15793583
Biological Process	GO:0034384	high-density lipoprotein particle clearance	Apom	IMP		Mouse	MGI:MGI:3575626|PMID:15793583
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	APOM	IMP		Human	PMID:18006500
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	Apom	IMP		Mouse	MGI:MGI:3575626|PMID:15793583
Biological Process	GO:0042157	lipoprotein metabolic process	Apom	IMP		Mouse	PMID:15793583
Biological Process	GO:0034445	negative regulation of plasma lipoprotein oxidation	APOM	IDA		Human	PMID:16682745
Biological Process	GO:0034445	negative regulation of plasma lipoprotein oxidation	APOM	IDA		Human	PMID:22204862
Biological Process	GO:0034445	negative regulation of plasma lipoprotein oxidation	Apom	IDA		Mouse	MGI:MGI:5427066|PMID:22204862
Biological Process	GO:0009749	response to glucose	Apom	IEP		Rat	PMID:17556016|RGD:2313117
Biological Process	GO:0043691	reverse cholesterol transport	Apom	IMP		Mouse	PMID:15793583

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern