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Gene Ontology Browser
Term Detail
GO term:low-density lipoprotein particle
Synonym: LDL complex
Synonym: LDL particle
Synonym: low-density lipoprotein complex
GO id:GO:0034362
Definition:A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-aextracellular region
                        part-ofextracellular region part
                                is-aextracellular space
                                        part-ofplasma lipoprotein particle
                                                is-achylomicron +
                                                is-ahigh-density lipoprotein particle +
                                                is-alow-density lipoprotein particle [GO:0034362] (12 genes, 13 annotations)
                                                is-atriglyceride-rich lipoprotein particle +


Gene_Ontology
        is-acellular_component
                is-aextracellular region
                        part-ofextracellular region part
                                is-aplasma lipoprotein particle
                                        is-achylomicron +
                                        is-ahigh-density lipoprotein particle +
                                        is-alow-density lipoprotein particle [GO:0034362] (12 genes, 13 annotations)
                                        is-atriglyceride-rich lipoprotein particle +


Gene_Ontology
        is-acellular_component
                is-aextracellular region part
                        is-aextracellular space
                                part-ofplasma lipoprotein particle
                                        is-achylomicron +
                                        is-ahigh-density lipoprotein particle +
                                        is-alow-density lipoprotein particle [GO:0034362] (12 genes, 13 annotations)
                                        is-atriglyceride-rich lipoprotein particle +


Gene_Ontology
        is-acellular_component
                is-aextracellular region part
                        is-aplasma lipoprotein particle
                                is-achylomicron +
                                is-ahigh-density lipoprotein particle +
                                is-alow-density lipoprotein particle [GO:0034362] (12 genes, 13 annotations)
                                is-atriglyceride-rich lipoprotein particle +


Gene_Ontology
        is-acellular_component
                is-amacromolecular complex
                        is-aprotein-lipid complex
                                is-aplasma lipoprotein particle
                                        is-achylomicron +
                                        is-ahigh-density lipoprotein particle +
                                        is-alow-density lipoprotein particle [GO:0034362] (12 genes, 13 annotations)
                                        is-atriglyceride-rich lipoprotein particle +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory