Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APBA2
  • Mouse genes Apba2
  • Rat genes Apba2
  • Zfish genes apba2a,apba2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apba2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	Apba2	IPI	RGD:736021	Rat	PMID:12196555|RGD:1302262
Molecular Function	GO:0042802	identical protein binding	APBA2	IPI	UniProtKB:Q99767	Human	PMID:29578633
Molecular Function	GO:0005515	protein binding	APBA2	IPI	UniProtKB:Q96P71	Human	PMID:10833507
Molecular Function	GO:0005515	protein binding	APBA2	IPI	UniProtKB:O94985	Human	PMID:17332754
Molecular Function	GO:0005515	protein binding	APBA2	IPI	UniProtKB:O94985	Human	PMID:29578633
Molecular Function	GO:0005515	protein binding	APBA2	IPI	UniProtKB:P05067	Human	PMID:29578633
Molecular Function	GO:0005515	protein binding	APBA2	IPI	UniProtKB:P05067	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	Apba2	IPI	UniProtKB:P12023	Mouse	MGI:MGI:5315676|PMID:20925061
Molecular Function	GO:0005515	protein binding	Apba2	IPI	UniProtKB:P12023	Mouse	MGI:MGI:3688062|PMID:11517249
Molecular Function	GO:0005515	protein binding	Apba2	IPI	UniProtKB:P49768	Mouse	MGI:MGI:5493220|PMID:11083918
Molecular Function	GO:0005515	protein binding	Apba2	IPI	PR:Q9D6J4	Mouse	PMID:10833507
Molecular Function	GO:0005515	protein binding	Apba2	IPI	RGD:731724	Rat	PMID:12196555|RGD:1302262
Molecular Function	GO:0005515	protein binding	Apba2	IPI	UniProtKB:Q8R4T5	Rat	PMID:12586822|RGD:1299234
Molecular Function	GO:0005515	protein binding	Apba2	IPI	RGD:620144	Rat	PMID:19265194|RGD:5684374
Molecular Function	GO:0005515	protein binding	Apba2	IPI	UniProtKB:P05067	Rat	PMID:22730553|RGD:14995319
Molecular Function	GO:0005515	protein binding	Apba2	IPI	RGD:3785	Rat	PMID:9395480|RGD:727250
Molecular Function	GO:0005515	protein binding	Apba2	IPI	UniProtKB:P61765	Rat	PMID:9395480|RGD:727250
Cellular Component	GO:0005886	plasma membrane	Apba2	IDA		Rat	PMID:9395480|RGD:727250
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Apba2	IMP		Mouse	PMID:17167098
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Apba2	IDA		Mouse	PMID:17167098
Biological Process	GO:0007268	chemical synaptic transmission	Apba2	IGI	MGI:MGI:1888527	Mouse	PMID:17167098
Biological Process	GO:0007268	chemical synaptic transmission	Apba2	IGI	MGI:MGI:1860297	Mouse	PMID:17167098
Biological Process	GO:0001701	in utero embryonic development	Apba2	IGI	MGI:MGI:1860297	Mouse	PMID:17167098
Biological Process	GO:0007626	locomotory behavior	Apba2	IGI	MGI:MGI:1860297	Mouse	PMID:17167098
Biological Process	GO:0035264	multicellular organism growth	Apba2	IGI	MGI:MGI:1860297	Mouse	PMID:17167098
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Apba2	IDA		Mouse	PMID:17167098
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Apba2	IMP		Mouse	PMID:17167098
Biological Process	GO:0010468	regulation of gene expression	Apba2	IGI	MGI:MGI:1860297	Mouse	PMID:17167098
Biological Process	GO:0010468	regulation of gene expression	Apba2	IGI	MGI:MGI:1888527	Mouse	PMID:17167098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern