Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APBA1
  • Mouse genes Apba1
  • Rat genes Apba1
  • Zfish genes apba1a,apba1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apba1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	Apba1	IPI	RGD:736021	Rat	PMID:12196555|RGD:1302262
Molecular Function	GO:0030165	PDZ domain binding	Apba1	IPI	RGD:621660	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Apba1	IDA		Rat	PMID:9395480|RGD:727250
Molecular Function	GO:0005515	protein binding	APBA1	IPI	UniProtKB:P49768	Human	PMID:11083918
Molecular Function	GO:0005515	protein binding	APBA1	IPI	UniProtKB:P49768	Human	PMID:16007100
Molecular Function	GO:0005515	protein binding	APBA1	IPI	UniProtKB:O95073	Human	PMID:20531236
Molecular Function	GO:0005515	protein binding	APBA1	IPI	UniProtKB:P05067	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	APBA1	IPI	UniProtKB:P05067	Human	PMID:8887653
Molecular Function	GO:0005515	protein binding	Apba1	IPI	PR:O88952	Mouse	PMID:16186258
Molecular Function	GO:0005515	protein binding	Apba1	IPI	PR:O70589	Mouse	PMID:18054859
Molecular Function	GO:0005515	protein binding	Apba1	IPI	RGD:731724	Rat	PMID:12196555|RGD:1302262
Molecular Function	GO:0005515	protein binding	Apba1	IPI	RGD:620730	Rat	PMID:14960569|RGD:1304295
Molecular Function	GO:0005515	protein binding	Apba1	IPI	UniProtKB:P32851	Rat	PMID:16763567|RGD:8553578
Molecular Function	GO:0005515	protein binding	Apba1	IPI	RGD:3785	Rat	PMID:9395480|RGD:727250
Molecular Function	GO:0005515	protein binding	Apba1	IPI	UniProtKB:P32851	Rat	PMID:9395480|RGD:727250
Molecular Function	GO:0005515	protein binding	Apba1	IPI	UniProtKB:P61765	Rat	PMID:9395480|RGD:727250
Molecular Function	GO:0019901	protein kinase binding	Apba1	IPI	RGD:62004	Rat	PMID:17084383|RGD:2326120
Molecular Function	GO:0044877	protein-containing complex binding	Apba1	IDA		Rat	PMID:9395480|RGD:727250
Cellular Component	GO:0043197	dendritic spine	Apba1	IDA		Rat	PMID:25378388|RGD:10047276
Cellular Component	GO:0098978	glutamatergic synapse	Apba1	IDA		Mouse	PMID:10971649
Cellular Component	GO:0098978	glutamatergic synapse	Apba1	IMP		Mouse	PMID:17167098
Cellular Component	GO:0098978	glutamatergic synapse	Apba1	IDA		Mouse	PMID:17167098
Cellular Component	GO:0005794	Golgi apparatus	APBA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Apba1	IDA		Mouse	PMID:18054859
Cellular Component	GO:0016020	membrane	Apba1	IDA		Rat	PMID:17084383|RGD:2326120
Cellular Component	GO:0005886	plasma membrane	Apba1	IDA		Rat	PMID:9395480|RGD:727250
Cellular Component	GO:0048787	presynaptic active zone membrane	Apba1	IDA		Mouse	PMID:10971649
Cellular Component	GO:0032991	protein-containing complex	Apba1	IDA		Rat	PMID:9395480|RGD:727250
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Apba1	IMP		Mouse	PMID:17167098
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Apba1	IDA		Mouse	PMID:17167098
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Apba1	IMP		Mouse	PMID:12547917
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Apba1	IDA		Mouse	PMID:12547917
Biological Process	GO:0007268	chemical synaptic transmission	Apba1	IGI	MGI:MGI:1261791	Mouse	PMID:17167098
Biological Process	GO:0007268	chemical synaptic transmission	Apba1	IGI	MGI:MGI:1888527	Mouse	PMID:17167098
Biological Process	GO:0007268	chemical synaptic transmission	Apba1	IMP	MGI:MGI:2450729	Mouse	PMID:17167098
Biological Process	GO:0051649	establishment of localization in cell	Apba1	IGI	MGI:MGI:1261791	Mouse	PMID:17167098
Biological Process	GO:0051649	establishment of localization in cell	Apba1	IMP	MGI:MGI:2450729	Mouse	PMID:17167098
Biological Process	GO:0014051	gamma-aminobutyric acid secretion	Apba1	IMP	MGI:MGI:2450729	Mouse	PMID:17167098
Biological Process	GO:0014047	glutamate secretion	Apba1	IGI	MGI:MGI:1261791	Mouse	PMID:17167098
Biological Process	GO:0001701	in utero embryonic development	Apba1	IGI	MGI:MGI:1261791	Mouse	PMID:17167098
Biological Process	GO:0001701	in utero embryonic development	Apba1	IGI	MGI:MGI:1888527	Mouse	PMID:17167098
Biological Process	GO:0006886	intracellular protein transport	Apba1	IPI	PR:O70589	Mouse	PMID:9822620
Biological Process	GO:0007626	locomotory behavior	Apba1	IGI	MGI:MGI:1261791	Mouse	PMID:17167098
Biological Process	GO:0035264	multicellular organism growth	Apba1	IGI	MGI:MGI:1261791	Mouse	PMID:17167098
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Apba1	IDA		Mouse	PMID:17167098
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Apba1	IMP		Mouse	PMID:17167098
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Apba1	IDA		Mouse	PMID:12547917
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Apba1	IMP		Mouse	PMID:12547917
Biological Process	GO:0010468	regulation of gene expression	Apba1	IGI	MGI:MGI:1261791	Mouse	PMID:17167098
Biological Process	GO:0010468	regulation of gene expression	Apba1	IGI	MGI:MGI:1888527	Mouse	PMID:17167098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern