Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH3A1
  • Mouse genes Aldh3a1
  • Rat genes Aldh3a1
  • Zfish genes aldh3a1,aldh3a2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh3a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	Aldh3a1	IDA		Mouse	PMID:12610736
Molecular Function	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	Aldh3a1	IDA		Mouse	PMID:742739
Molecular Function	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	Aldh3a1	IMP	MGI:MGI:2180794	Mouse	PMID:11784860
Molecular Function	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	Aldh3a1	IDA		Rat	PMID:2831537|RGD:632185
Molecular Function	GO:0008106	alcohol dehydrogenase (NADP+) activity	ALDH3A1	IDA		Human	PMID:1737758
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH3A1	IDA		Human	PMID:1737758
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	Aldh3a1	IDA		Mouse	PMID:25286108
Molecular Function	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity	ALDH3A1	IDA		Human	PMID:4015840
Molecular Function	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Aldh3a1	IDA		Mouse	MGI:MGI:1341968|PMID:10376761
Molecular Function	GO:0005515	protein binding	ALDH3A1	IPI	UniProtKB:Q9NUX5	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ALDH3A1	IPI	UniProtKB:O75344	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Aldh3a1	IDA		Mouse	PMID:25286108
Cellular Component	GO:0005737	cytoplasm	Aldh3a1	IDA		Rat	PMID:8617795|RGD:2300318
Cellular Component	GO:0005829	cytosol	ALDH3A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Aldh3a1	IDA		Rat	PMID:11306046|RGD:8554812
Cellular Component	GO:0005783	endoplasmic reticulum	ALDH3A1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005615	extracellular space	ALDH3A1	HDA		Human	PMID:22664934
Cellular Component	GO:0016020	membrane	Aldh3a1	IDA		Mouse	PMID:25286108
Cellular Component	GO:0005886	plasma membrane	ALDH3A1	IDA		Human	GO_REF:0000052
Biological Process	GO:0007568	aging	Aldh3a1	IEP		Rat	PMID:16291827|RGD:2300311
Biological Process	GO:0006081	cellular aldehyde metabolic process	ALDH3A1	IDA		Human	PMID:1737758
Biological Process	GO:0042593	glucose homeostasis	aldh3a1	IMP	ZFIN:ZDB-GENO-220811-4	Zfish	PMID:32980661
Biological Process	GO:0008284	positive regulation of cell population proliferation	Aldh3a1	IMP		Rat	PMID:12604187|RGD:2300313
Biological Process	GO:0051591	response to cAMP	Aldh3a1	IDA		Rat	PMID:9013560|RGD:2300317
Biological Process	GO:0051384	response to glucocorticoid	Aldh3a1	IDA		Rat	PMID:10101022|RGD:2300316
Biological Process	GO:0001666	response to hypoxia	Aldh3a1	IDA		Rat	PMID:11306047|RGD:2300314
Biological Process	GO:0007584	response to nutrient	Aldh3a1	IEP		Rat	PMID:7751973|RGD:2300308
Biological Process	GO:0014070	response to organic cyclic compound	Aldh3a1	IEP		Rat	PMID:12604189|RGD:2300312
Biological Process	GO:0014070	response to organic cyclic compound	Aldh3a1	IDA		Rat	PMID:18203689|RGD:2300310
Biological Process	GO:0009410	response to xenobiotic stimulus	Aldh3a1	IDA		Rat	PMID:10323327|RGD:2300315
Biological Process	GO:0009410	response to xenobiotic stimulus	Aldh3a1	IEP		Rat	PMID:10323328|RGD:2306338

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern