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Aldh3a1
Gene Detail
 Symbol
Name
ID
Aldh3a1
aldehyde dehydrogenase family 3, subfamily A1
MGI:1353451
Synonyms Ahd4, Ahd-4, Aldh, Aldh3
Feature Type protein coding gene
Genetic Map
Chromosome 11
37.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(21)
Sequence Map
Chr11:61207537-61218421 bp, + strand
From VEGA annotation of GRCm38

  10885 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20175  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: aldehyde dehydrogenase
Gene Tree: Aldh3a1

Human
homologs
Human Homolog ALDH3A1, aldehyde dehydrogenase 3 family, member A1
NCBI Gene ID 218
neXtProt AC  NX_P30838
Human Synonyms  ALDH3, ALDHIII
Human Chr (Location)  17p11.2; chr17:19737984-19748433 (-)  GRCh38
Alleles
and
phenotypes
All alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene does not result in a phenotype.
 
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process cellular aldehyde metabolic process, metabolic process, ...
Component cytoplasm, cytosol, ...
Function 3-chloroallyl aldehyde dehydrogenase activity, alcohol dehydrogenase (NADP+) activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (109)    Tissues (109)   
Theiler Stages: 1, 3, 4, 15, 19, 22, 28
Assay TypeResults
RNA in situ 99
RT-PCR 10
cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005823 (Evidence)
Ensembl Gene ModelENSMUSG00000019102 (Evidence)
Entrez Gene11670 (Evidence)
UniGene4257
DFCITC1580393
DoTSDT.101267303, DT.60118128
NIA Mouse Gene IndexU012717
EC1.2.1.5
Consensus CDS ProjectCCDS24808.1
International Mouse Knockout Project StatusAldh3a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005823 VEGA Gene Model | MGI Sequence Detail 10885 C57BL/6J ±  kb
transcript OTTMUST00000012919 VEGA | MGI Sequence Detail 1721 Not Applicable 
polypeptide OTTMUSP00000006009 VEGA | MGI Sequence Detail 453 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(16) UniProt(4)
Polymorphisms RFLP(2) : SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016160 Aldehyde dehydrogenase, conserved site
InterPro IPR016163 Aldehyde dehydrogenase, C-terminal
InterPro IPR015590 Aldehyde dehydrogenase domain
InterPro IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
InterPro IPR016162 Aldehyde dehydrogenase, N-terminal
InterPro IPR016161 Aldehyde/histidinol dehydrogenase
Protein Ontology PR:000003926 aldehyde dehydrogenase, dimeric NADP-preferring
References (Earliest) J:6092 Lush IE, Genetic variation of some aldehyde-oxidizing enzymes in the mouse. Anim Blood Groups Biochem Genet. 1978;9(2):85-96
(Latest) J:191504 Gasparetto M, et al., Aldehyde dehydrogenases are regulators of hematopoietic stem cell numbers and B-cell development. Exp Hematol. 2012 Apr;40(4):318-29.e2
All references(71)
Other
accession IDs
MGD-MRK-1209, MGD-MRK-1216, MGD-MRK-1275, MGD-MRK-16381, MGI:87993, MGI:99599

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory