Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABR
  • Mouse genes Abr
  • Rat genes Abr
  • Zfish genes abr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	ABR	IDA		Human	PMID:7479768
Molecular Function	GO:0005096	GTPase activator activity	Abr	IDA		Mouse	PMID:17116687
Molecular Function	GO:0005096	GTPase activator activity	Abr	IGI	MGI:MGI:88141	Mouse	PMID:19703997
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ABR	IDA		Human	PMID:7479768
Molecular Function	GO:0005515	protein binding	ABR	IPI	UniProtKB:P78352	Human	PMID:20962234
Molecular Function	GO:0005515	protein binding	Abr	IPI	UniProtKB:P31016	Rat	PMID:20962234|RGD:13702252
Cellular Component	GO:0005829	cytosol	Abr	IDA		Mouse	PMID:17116687
Cellular Component	GO:0098978	glutamatergic synapse	Abr	IDA		Mouse	PMID:20962234
Cellular Component	GO:0098978	glutamatergic synapse	Abr	IMP		Mouse	PMID:20962234
Cellular Component	GO:0098978	glutamatergic synapse	Abr	IDA		Rat	PMID:20962234|RGD:13702252
Cellular Component	GO:0016020	membrane	ABR	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	Abr	IDA		Mouse	PMID:17116687
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Abr	IDA		Rat	PMID:20962234|RGD:13702252
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Abr	IDA		Mouse	PMID:20962234
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Abr	IMP		Mouse	PMID:20962234
Biological Process	GO:0030036	actin cytoskeleton organization	Abr	IGI	MGI:MGI:88141	Mouse	PMID:17116687
Biological Process	GO:0090630	activation of GTPase activity	ABR	IDA		Human	PMID:7479768
Biological Process	GO:0007420	brain development	Abr	IGI	MGI:MGI:88141	Mouse	PMID:11684658
Biological Process	GO:0016477	cell migration	Abr	IGI	MGI:MGI:88141	Mouse	PMID:17116687
Biological Process	GO:0051649	establishment of localization in cell	Abr	IGI	MGI:MGI:88141	Mouse	PMID:17116687
Biological Process	GO:0042472	inner ear morphogenesis	Abr	IGI	MGI:MGI:88141	Mouse	PMID:11921339
Biological Process	GO:1905517	macrophage migration	Abr	IGI	MGI:MGI:88141	Mouse	PMID:17116687
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Abr	IDA		Mouse	PMID:20962234
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Abr	IMP		Mouse	PMID:20962234
Biological Process	GO:0060313	negative regulation of blood vessel remodeling	Abr	IMP		Mouse	MGI:MGI:5475443|PMID:23152932
Biological Process	GO:0002692	negative regulation of cellular extravasation	Abr	IMP		Mouse	MGI:MGI:5475443|PMID:23152932
Biological Process	GO:0050728	negative regulation of inflammatory response	Abr	IMP	MGI:MGI:2388713	Mouse	PMID:19703997
Biological Process	GO:1905522	negative regulation of macrophage migration	Abr	IGI	MGI:MGI:88141	Mouse	PMID:17116687
Biological Process	GO:0043314	negative regulation of neutrophil degranulation	Abr	IGI	MGI:MGI:88141	Mouse	PMID:19703997
Biological Process	GO:0050885	neuromuscular process controlling balance	Abr	IGI	MGI:MGI:88141	Mouse	PMID:11921339
Biological Process	GO:0043312	neutrophil degranulation	Abr	IGI	MGI:MGI:88141	Mouse	PMID:19703997
Biological Process	GO:0006909	phagocytosis	Abr	IGI	MGI:MGI:88141	Mouse	PMID:17116687
Biological Process	GO:0050766	positive regulation of phagocytosis	Abr	IGI	MGI:MGI:88141	Mouse	PMID:17116687
Biological Process	GO:0043114	regulation of vascular permeability	Abr	IMP		Mouse	MGI:MGI:5475443|PMID:23152932
Biological Process	GO:0032496	response to lipopolysaccharide	Abr	IMP	MGI:MGI:2388713	Mouse	PMID:19703997

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern