| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | Hirschsprung's disease | EDN3* | Edn3* | 2 models | Alliance of Genome Resources | ||
| Hirschsprung's disease | RET* | Ret* | 4 models | Alliance of Genome Resources | |||
| Hirschsprung's disease | GDNF* | Gdnf* | 3 models | Alliance of Genome Resources | |||
| Hirschsprung's disease | EDNRB* | Ednrb* | 5 models | Alliance of Genome Resources | |||
| | colonic disease | SAV1 | Sav1* | 1 model | Alliance of Genome Resources | ||
| Hirschsprung's disease | ITGB1 | Itgb1* | 1 model | Alliance of Genome Resources | |||
| Hirschsprung's disease | IHH | Ihh* | 1 model | Alliance of Genome Resources | |||
| Hirschsprung's disease | GFRA1 | Gfra1* | 2 models | Alliance of Genome Resources | |||
| Hirschsprung's disease | ERBB2 | Erbb2* | 1 model | Alliance of Genome Resources | |||
| Hirschsprung's disease | AEBP2 | Aebp2* | 1 model | Alliance of Genome Resources | |||
| intestinal pseudo-obstruction | SPRY2 | Spry2* | 1 model | Alliance of Genome Resources | |||
| intestinal pseudo-obstruction | NUP35 | Nup35* | 1 model | Alliance of Genome Resources | |||
| intestinal pseudo-obstruction | PTEN | Pten* | 1 model | Alliance of Genome Resources | |||
| intestinal pseudo-obstruction | TLX2 | Tlx2* | 2 models | Alliance of Genome Resources | |||
| | ascending colon cancer | POLE* | Pole | Alliance of Genome Resources | |||
| ascending colon cancer | RNF43* | Rnf43 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | STAT6* | Stat6 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | STAT5B* | Stat5b | Alliance of Genome Resources | ||||
| colon adenocarcinoma | STAT5A* | Stat5a | Alliance of Genome Resources | ||||
| colon adenocarcinoma | STAT3* | Stat3 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | STAT1* | Stat1 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | SRC* | Src | Alliance of Genome Resources | ||||
| colon adenocarcinoma | SMC2* | Smc2 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | RNASET2* | Rnaset2a, Rnaset2b | Alliance of Genome Resources | ||||
| colon adenocarcinoma | RAC1* | Rac1 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | PIK3R3* | Pik3r3 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | PIK3CA* | Pik3ca | Alliance of Genome Resources | ||||
| colon adenocarcinoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | MIR155* | Mir155 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | MAPK3* | Mapk3 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | MAPK1* | Mapk1 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | MAP2K7* | Map2k7 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | LOX* | Lox | Alliance of Genome Resources | ||||
| colon adenocarcinoma | KDM6A* | Kdm6a | Alliance of Genome Resources | ||||
| colon adenocarcinoma | JAK2* | Jak2 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | GATA1* | Gata1 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | CSF1R* | Csf1r | Alliance of Genome Resources | ||||
| colon adenocarcinoma | CHD4* | Chd4 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | BAX* | Bax | Alliance of Genome Resources | ||||
| colon adenocarcinoma | ABHD5* | Abhd5 | Alliance of Genome Resources | ||||
| colon adenocarcinoma | UBR5* | Ubr5 | Alliance of Genome Resources | ||||
| colon cancer | PRKAA1* | Prkaa1 | Alliance of Genome Resources | ||||
| colon cancer | ACVR2A* | Acvr2a | Alliance of Genome Resources | ||||
| colon cancer | ADA* | Ada | Alliance of Genome Resources | ||||
| colon cancer | AKT1* | Akt1 | Alliance of Genome Resources | ||||
| colon cancer | AKT3* | Akt3 | Alliance of Genome Resources | ||||
| colon cancer | ARID1A* | Arid1a | Alliance of Genome Resources | ||||
| colon cancer | ATR* | Atr | Alliance of Genome Resources | ||||
| colon cancer | BIK* | Bik | Alliance of Genome Resources | ||||
| colon cancer | BRCA1* | Brca1 | Alliance of Genome Resources | ||||
| colon cancer | BRD4* | Brd4 | Alliance of Genome Resources | ||||
| colon cancer | CALR* | Calr | Alliance of Genome Resources | ||||
| colon cancer | CASP3* | Casp3 | Alliance of Genome Resources | ||||
| colon cancer | CASP7* | Casp7 | Alliance of Genome Resources | ||||
| colon cancer | CHAF1A* | Chaf1a | Alliance of Genome Resources | ||||
| colon cancer | CRIPTO*, CRIPTO3 | Cripto | Alliance of Genome Resources | ||||
| colon cancer | CYP24A1* | Cyp24a1 | Alliance of Genome Resources | ||||
| colon cancer | HS3ST2* | Hs3st2 | Alliance of Genome Resources | ||||
| colon cancer | HTRA1* | Htra1 | Alliance of Genome Resources | ||||
| colon cancer | IL7R* | Il7r | Alliance of Genome Resources | ||||
| colon cancer | IL10* | Il10 | Alliance of Genome Resources | ||||
| colon cancer | KDM3A* | Kdm3a | Alliance of Genome Resources | ||||
| colon cancer | LRP1B* | Lrp1b | Alliance of Genome Resources | ||||
| colon cancer | MAPK14* | Mapk14 | Alliance of Genome Resources | ||||
| colon cancer | MIR193A* | Mir193a | Alliance of Genome Resources | ||||
| colon cancer | MRE11* | Mre11a | Alliance of Genome Resources | ||||
| colon cancer | MSH2* | Msh2 | Alliance of Genome Resources | ||||
| colon cancer | NCOA6* | Ncoa6 | Alliance of Genome Resources | ||||
| colon cancer | NEAT1* | Neat1 | Alliance of Genome Resources | ||||
| colon cancer | PIK3R5* | Pik3r5 | Alliance of Genome Resources | ||||
| colon cancer | PPARG* | Pparg | Alliance of Genome Resources | ||||
| colon cancer | PTPN13* | Ptpn13 | Alliance of Genome Resources | ||||
| colon cancer | RAD52* | Rad52 | Alliance of Genome Resources | ||||
| colon cancer | RICTOR* | Rictor | Alliance of Genome Resources | ||||
| colon cancer | SLC7A5* | Slc7a5 | Alliance of Genome Resources | ||||
| colon cancer | SRC* | Src | Alliance of Genome Resources | ||||
| colon cancer | TGFBR2* | Tgfbr2 | Alliance of Genome Resources | ||||
| colon carcinoma | CALR* | Calr | Alliance of Genome Resources | ||||
| colon carcinoma | BRAF* | Braf | Alliance of Genome Resources | ||||
| colon carcinoma | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| colon carcinoma | FLT3LG* | Flt3l | Alliance of Genome Resources | ||||
| colon carcinoma | EFNB2* | Efnb2 | Alliance of Genome Resources | ||||
| colon carcinoma | TNFRSF17* | Tnfrsf17 | Alliance of Genome Resources | ||||
| colon carcinoma | HPGD* | Hpgd | Alliance of Genome Resources | ||||
| colon carcinoma | TYMS* | Tyms | Alliance of Genome Resources | ||||
| colon carcinoma | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
| colonic disease | GHR* | Ghr | Alliance of Genome Resources | ||||
| descending colon cancer | KDM5C* | Kdm5c | Alliance of Genome Resources | ||||
| Hirschsprung's disease | SHH* | Shh | Alliance of Genome Resources | ||||
| Hirschsprung's disease | ZEB2* | Zeb2 | Alliance of Genome Resources | ||||
| Hirschsprung's disease | WNT8B* | Wnt8b | Alliance of Genome Resources | ||||
| Hirschsprung's disease | STX1A* | Stx1a | Alliance of Genome Resources | ||||
| Hirschsprung's disease | NRTN* | Nrtn | Alliance of Genome Resources | ||||
| Hirschsprung's disease | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| Hirschsprung's disease | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| neuronal intestinal dysplasia type A | ERBB3* | Erbb3 | Alliance of Genome Resources | ||||
| X-linked chronic idiopathic intestinal pseudo-obstruction | FLNA* | Flna | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| Hirschsprung's disease | Tg(Sox3-GFP,Tyr)HolNpln | 1 model | |
| Hirschsprung's disease | Tg(SRY-YFP,Tyr)TashTNpln | 1 model | |