| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
| Alport syndrome 2 | COL4A3* | Col4a3* | 5 models | Alliance of Genome Resources | ||
| Alport syndrome 2 | COL4A4* | Col4a4* | 5 models | Alliance of Genome Resources | |||
| autosomal dominant polycystic kidney disease | PKD2* | Pkd2* | 1 model | Alliance of Genome Resources | |||
| polycystic kidney disease 1 | PKD1* | Pkd1* | 28 models | Alliance of Genome Resources | |||
| polycystic kidney disease 2 | PKD2* | Pkd2* | 7 models | Alliance of Genome Resources | |||
| X-linked Alport syndrome | COL4A5* | Col4a5* | 3 models | Alliance of Genome Resources | |||
| Alport syndrome 2 | MPV17 | Mpv17* | 1 model | Alliance of Genome Resources | ||
| autosomal dominant polycystic kidney disease | BICC1 | Bicc1* | 1 model | Alliance of Genome Resources | |||
| autosomal dominant polycystic kidney disease | MYC | Myc* | 1 model | Alliance of Genome Resources | |||
| autosomal dominant polycystic kidney disease | NPHP3 | Nphp3* | 3 models | Alliance of Genome Resources | |||
| chronic kidney disease | ERMP1 | Ermp1* | 1 model | Alliance of Genome Resources | |||
| chronic kidney disease | RTN3 | Rtn3* | 1 model | Alliance of Genome Resources | |||
| end stage renal disease | CD2AP | Cd2ap* | 1 model | Alliance of Genome Resources | |||
| acute kidney failure | MPO* | Mpo | Alliance of Genome Resources | ||||
| acute kidney failure | PROC* | Proc | Alliance of Genome Resources | ||||
| acute kidney failure | ADRB2* | Adrb2 | Alliance of Genome Resources | ||||
| acute kidney failure | AGER* | Ager | Alliance of Genome Resources | ||||
| acute kidney failure | AMBP* | Ambp | Alliance of Genome Resources | ||||
| acute kidney failure | CRP* | Crp | Alliance of Genome Resources | ||||
| acute kidney failure | EPO* | Epo | Alliance of Genome Resources | ||||
| acute kidney failure | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| acute kidney failure | THBD* | Thbd | Alliance of Genome Resources | ||||
| acute kidney failure | SLC22A2* | Slc22a2 | Alliance of Genome Resources | ||||
| Alport syndrome | COL4A5* | Col4a5 | Alliance of Genome Resources | ||||
| Alport syndrome | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| Alport syndrome | COL4A3* | Col4a3 | Alliance of Genome Resources | ||||
| Alport syndrome 3A | COL4A3* | Col4a3 | Alliance of Genome Resources | ||||
| Alport syndrome 3A | MYH9* | Myh9 | Alliance of Genome Resources | ||||
| autosomal dominant polycystic kidney disease | PKD1* | Pkd1 | Alliance of Genome Resources | ||||
| autosomal dominant polycystic kidney disease | MTOR* | Mtor | Alliance of Genome Resources | ||||
| autosomal dominant polycystic kidney disease | LRP5* | Lrp5 | Alliance of Genome Resources | ||||
| chronic kidney disease | PTH* | Pth | Alliance of Genome Resources | ||||
| chronic kidney disease | AGER* | Ager | Alliance of Genome Resources | ||||
| chronic kidney disease | AGTR1* | Agtr1a, Agtr1b | Alliance of Genome Resources | ||||
| chronic kidney disease | AKAP12* | Akap12 | Alliance of Genome Resources | ||||
| chronic kidney disease | APOC3* | Apoc3 | Alliance of Genome Resources | ||||
| chronic kidney disease | COL6A3* | Col6a3 | Alliance of Genome Resources | ||||
| chronic kidney disease | CPB2* | Cpb2 | Alliance of Genome Resources | ||||
| chronic kidney disease | KLK1*, KLK2, KLK3 | Egfbp2, Klk1, Klk1b1, Klk1b3, Klk1b4, Klk1b5, Klk1b8, Klk1b9, Klk1b11, Klk1b16, Klk1b21, Klk1b22, Klk1b24, Klk1b26, Klk1b27 | Alliance of Genome Resources | ||||
| chronic kidney disease | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| chronic kidney disease | IL1B* | Il1b | Alliance of Genome Resources | ||||
| chronic kidney disease | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| chronic kidney disease | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| chronic kidney disease | SLC34A1* | Slc34a1 | Alliance of Genome Resources | ||||
| chronic kidney disease | TLR9* | Tlr9 | Alliance of Genome Resources | ||||
| chronic kidney disease | XDH* | Xdh | Alliance of Genome Resources | ||||
| end stage renal disease | GLO1* | Glo1 | Alliance of Genome Resources | ||||
| end stage renal disease | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| end stage renal disease | IL1A* | Il1a | Alliance of Genome Resources | ||||
| end stage renal disease | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| end stage renal disease | ITGA8* | Itga8 | Alliance of Genome Resources | ||||
| end stage renal disease | ITGB3* | Itgb3 | Alliance of Genome Resources | ||||
| end stage renal disease | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| end stage renal disease | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| end stage renal disease | MMP3* | Mmp3 | Alliance of Genome Resources | ||||
| end stage renal disease | MPO* | Mpo | Alliance of Genome Resources | ||||
| end stage renal disease | MSC* | Msc | Alliance of Genome Resources | ||||
| end stage renal disease | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| end stage renal disease | MYH9* | Myh9 | Alliance of Genome Resources | ||||
| end stage renal disease | NGF* | Ngf | Alliance of Genome Resources | ||||
| end stage renal disease | NOS3* | Nos3 | Alliance of Genome Resources | ||||
| end stage renal disease | PLAU* | Plau | Alliance of Genome Resources | ||||
| end stage renal disease | PPARG* | Pparg | Alliance of Genome Resources | ||||
| end stage renal disease | SLC9A5* | Slc9a5 | Alliance of Genome Resources | ||||
| end stage renal disease | UCP2* | Ucp2 | Alliance of Genome Resources | ||||
| end stage renal disease | VWF* | Vwf | Alliance of Genome Resources | ||||
| end stage renal disease | ZMIZ1* | Zmiz1 | Alliance of Genome Resources | ||||
| end stage renal disease | ADRB2* | Adrb2 | Alliance of Genome Resources | ||||
| end stage renal disease | ACE* | Ace | Alliance of Genome Resources | ||||
| end stage renal disease | COL4A4* | Col4a4 | Alliance of Genome Resources | ||||
| end stage renal disease | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| end stage renal disease | CXCR2* | Cxcr2 | Alliance of Genome Resources | ||||
| end stage renal disease | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| end stage renal disease | CYP2C8*, CYP2C9, CYP2C18, CYP2C19 | Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c40, Cyp2c50, Cyp2c54, Cyp2c55, Cyp2c65, Cyp2c66, Cyp2c67, Cyp2c68, Cyp2c69 | Alliance of Genome Resources | ||||
| end stage renal disease | DRD2* | Drd2 | Alliance of Genome Resources | ||||
| end stage renal disease | KLK1*, KLK2, KLK3 | Egfbp2, Klk1, Klk1b1, Klk1b3, Klk1b4, Klk1b5, Klk1b8, Klk1b9, Klk1b11, Klk1b16, Klk1b21, Klk1b22, Klk1b24, Klk1b26, Klk1b27 | Alliance of Genome Resources | ||||
| end stage renal disease | ENPP1* | Enpp1 | Alliance of Genome Resources | ||||
| end stage renal disease | F5* | F5 | Alliance of Genome Resources | ||||
| end stage renal disease | FABP2* | Fabp2 | Alliance of Genome Resources | ||||
| end stage renal disease | FGB* | Fgb | Alliance of Genome Resources | ||||
| end stage renal disease | GCKR* | Gckr | Alliance of Genome Resources | ||||
| end stage renal disease | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| end stage renal disease | CD40* | Cd40 | Alliance of Genome Resources | ||||
| end stage renal disease | CCL2*, CCL7, CCL8, CCL11, CCL13 | Ccl2, Ccl7, Ccl8, Ccl11, Ccl12 | Alliance of Genome Resources | ||||
| end stage renal disease | BDKRB1* | Bdkrb1 | Alliance of Genome Resources | ||||
| end stage renal disease | AGTR2* | Agtr2 | Alliance of Genome Resources | ||||
| end stage renal disease | CHGA* | Chga | Alliance of Genome Resources | ||||
| end stage renal disease | COL3A1* | Col3a1 | Alliance of Genome Resources | ||||
| end stage renal disease | COL4A3* | Col4a3 | Alliance of Genome Resources | ||||
| kidney failure | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
| kidney failure | GFER* | Gfer | Alliance of Genome Resources | ||||
| kidney failure | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| kidney failure | DRD1* | Drd1 | Alliance of Genome Resources | ||||
| polycystic kidney disease 3 | GANAB* | Ganab | Alliance of Genome Resources | ||||
| polycystic kidney disease 6 | DNAJB11* | Dnajb11 | Alliance of Genome Resources | ||||
| polycystic kidney disease 7 | ALG5* | Alg5 | Alliance of Genome Resources | ||||
| uremia | COMT* | Comt | Alliance of Genome Resources | ||||
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| autosomal dominant polycystic kidney disease | Tg(HBB-Myc)#Cos | 1 model | |
| polycystic kidney disease 1 | Tg(Pkd1*)39Mtru | 2 models | |
| polycystic kidney disease 2 | Tg(CAG-PKD2)#Hwl | 1 model | |