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Gene Expression Data
Assay Details
Assay
Reference: J:308820 Shohayeb B, et al., The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus. Front Cell Dev Biol. 2020;8:549353
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7834526
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen S2A/A': embryonic day 17.5 (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:7834523).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus ventricular layer radial glial cell Present S2A' , S2A
Specimen S2B/B': embryonic day 17.5; Wdr62em3Dng/Wdr62em3Dng (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:7834523).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus ventricular layer radial glial cell Present S2B , S2B' Reduced expression compared with the wild-type.
Specimen S2C/C': embryonic day 17.5; Wdr62em1Dng/Wdr62em1Dng (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:7834523).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus ventricular layer radial glial cell Present S2C' , S2C Reduced expression compared with the wild-type.
Specimen S2D/D': embryonic day 17.5; Wdr62em2Dng/Wdr62em2Dng (more )
Note: Double labeled: red - Sox2; green - Eomes (assay MGI:7834523).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus ventricular layer radial glial cell Present S2D , S2D' Reduced expression compared with the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory