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Gene Expression Data
Assay Details
Assay
Reference: J:308820 Shohayeb B, et al., The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus. Front Cell Dev Biol. 2020;8:549353
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7834523
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-Eomes (Dan11mag, 50-4875-82,14-4875-80)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: embryonic day 17.5 (more )
Note: Triple labeled: green - Eomes; red - Pax6 (assay MGI:7834524); magenta - Tbr1 (assay MGI:7834522).
Structure Level Pattern Image Note
TS25: hippocampus ventricular layer Present 3A , 3A' Expressed in intermediate progenitors.
Specimen 3B: embryonic day 17.5; Wdr62em3Dng/Wdr62em3Dng (more )
Note: Triple labeled: green - Eomes; red - Pax6 (assay MGI:7834524); magenta - Tbr1 (assay MGI:7834522).
Structure Level Pattern Image Note
TS25: hippocampus ventricular layer Present 3B , 3B' Reduced expression in intermediate progenitors, compared with the wild-type.
Specimen 3C: embryonic day 17.5; Wdr62em1Dng/Wdr62em1Dng (more )
Note: Triple labeled: green - Eomes; red - Pax6 (assay MGI:7834524); magenta - Tbr1 (assay MGI:7834522).
Structure Level Pattern Image Note
TS25: hippocampus ventricular layer Present 3C , 3C' Reduced expression in intermediate progenitors, compared with the wild-type.
Specimen 3D: embryonic day 17.5; Wdr62em2Dng/Wdr62em2Dng (more )
Note: Triple labeled: green - Eomes; red - Pax6 (assay MGI:7834524); magenta - Tbr1 (assay MGI:7834522).
Structure Level Pattern Image Note
TS25: hippocampus ventricular layer Present 3D , 3D' Reduced expression in intermediate progenitors, compared with the wild-type.
Specimen S2A/A': embryonic day 17.5 (more )
Note: Double labeled: green - Eomes; red - Sox2 (assay MGI:7834526).
Structure Level Pattern Image Note
TS25: hippocampus ventricular layer Present S2A' , S2A Expressed in intermediate progenitors.
Specimen S2B/B': embryonic day 17.5; Wdr62em3Dng/Wdr62em3Dng (more )
Note: Double labeled: green - Eomes; red - Sox2 (assay MGI:7834526).
Structure Level Pattern Image Note
TS25: hippocampus ventricular layer Present S2B , S2B' Reduced expression in intermediate progenitors, compared with the wild-type.
Specimen S2C/C': embryonic day 17.5; Wdr62em1Dng/Wdr62em1Dng (more )
Note: Double labeled: green - Eomes; red - Sox2 (assay MGI:7834526).
Structure Level Pattern Image Note
TS25: hippocampus ventricular layer Present S2C , S2C' Reduced expression in intermediate progenitors, compared with the wild-type.
Specimen S2D/D': embryonic day 17.5; Wdr62em2Dng/Wdr62em2Dng (more )
Note: Double labeled: green - Eomes; red - Sox2 (assay MGI:7834526).
Structure Level Pattern Image Note
TS25: hippocampus ventricular layer Present S2D , S2D' Reduced expression in intermediate progenitors, compared with the wild-type.
Specimen S3A: embryonic day 15.5 (more )
Note: Triple labeled: green - Eomes; red - Pax6 (assay MGI:7834524); magenta - Tbr1 (assay MGI:7834522).
Structure Level Pattern Image Note
TS23: hippocampus Present S3A , S3A' Expressed in intermediate progenitors.
Specimen S3B: embryonic day 15.5; Wdr62em3Dng/Wdr62em3Dng (more )
Note: Triple labeled: green - Eomes; red - Pax6 (assay MGI:7834524); magenta - Tbr1 (assay MGI:7834522).
Structure Level Pattern Image Note
TS23: hippocampus Present S3B , S3B' Expressed in intermediate progenitors. Reduced expression in the ventricular layer, compared with the wild-type.
Specimen S3C: embryonic day 15.5; Wdr62em1Dng/Wdr62em1Dng (more )
Note: Triple labeled: green - Eomes; red - Pax6 (assay MGI:7834524); magenta - Tbr1 (assay MGI:7834522).
Structure Level Pattern Image Note
TS23: hippocampus Present S3C' , S3C Expressed in intermediate progenitors. Reduced expression in the ventricular layer, compared with the wild-type.
Specimen S3D: embryonic day 15.5; Wdr62em2Dng/Wdr62em2Dng (more )
Note: Triple labeled: green - Eomes; red - Pax6 (assay MGI:7834524); magenta - Tbr1 (assay MGI:7834522).
Structure Level Pattern Image Note
TS23: hippocampus Present S3D , S3D' Expressed in intermediate progenitors. Reduced expression in the ventricular layer, compared with the wild-type.
Specimen S4A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: dentate gyrus Present S4A Expressed in intermediate progenitors in the dentate migratory stream.
Specimen S4B: embryonic day 17.5; Wdr62em3Dng/Wdr62em3Dng (more )
Structure Level Pattern Image Note
TS25: dentate gyrus Present S4B Expressed in intermediate progenitors in the dentate migratory stream, similar as in the wild-type.
Specimen S4C: embryonic day 17.5; Wdr62em1Dng/Wdr62em1Dng (more )
Structure Level Pattern Image Note
TS25: dentate gyrus Present S4C Expressed in intermediate progenitors in the dentate migratory stream, similar as in the wild-type.
Specimen S4D: embryonic day 17.5; Wdr62em2Dng/Wdr62em2Dng (more )
Structure Level Pattern Image Note
TS25: dentate gyrus Present S4D Expressed in intermediate progenitors in the dentate migratory stream, similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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