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Gene Expression Data
Assay Details
Assay
Reference: J:308820 Shohayeb B, et al., The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus. Front Cell Dev Biol. 2020;8:549353
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7834524
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 3A: embryonic day 17.5 (more )
Note: Triple labeled: red - Pax6; green - Eomes (assay MGI:7834523); magenta - Tbr1 (assay MGI:7834522).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus ventricular layer radial glial cell Present 3A' , 3A
Specimen 3B: embryonic day 17.5; Wdr62em3Dng/Wdr62em3Dng (more )
Note: Triple labeled: red - Pax6; green - Eomes (assay MGI:7834523); magenta - Tbr1 (assay MGI:7834522).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus ventricular layer radial glial cell Present 3B , 3B' Reduced expression compared with the wild-type.
Specimen 3C: embryonic day 17.5; Wdr62em1Dng/Wdr62em1Dng (more )
Note: Triple labeled: red - Pax6; green - Eomes (assay MGI:7834523); magenta - Tbr1 (assay MGI:7834522).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus ventricular layer radial glial cell Present 3C , 3C' Reduced expression compared with the wild-type.
Specimen 3D: embryonic day 17.5; Wdr62em2Dng/Wdr62em2Dng (more )
Note: Triple labeled: red - Pax6; green - Eomes (assay MGI:7834523); magenta - Tbr1 (assay MGI:7834522).
Structure Cell Type Level Pattern Image Note
TS25: hippocampus ventricular layer radial glial cell Present 3D , 3D' Reduced expression compared with the wild-type.
Specimen S3A: embryonic day 15.5 (more )
Note: Triple labeled: red - Pax6; green - Eomes (assay MGI:7834523); magenta - Tbr1 (assay MGI:7834522).
Structure Cell Type Level Pattern Image Note
TS23: hippocampus radial glial cell Present Regionally restricted S3A , S3A' Expressed in the ventricular layer.
Specimen S3B: embryonic day 15.5; Wdr62em3Dng/Wdr62em3Dng (more )
Note: Triple labeled: red - Pax6; green - Eomes (assay MGI:7834523); magenta - Tbr1 (assay MGI:7834522).
Structure Cell Type Level Pattern Image Note
TS23: hippocampus radial glial cell Present Regionally restricted S3B , S3B' Reduced expression in the ventricular layer.
Specimen S3C: embryonic day 15.5; Wdr62em1Dng/Wdr62em1Dng (more )
Note: Triple labeled: red - Pax6; green - Eomes (assay MGI:7834523); magenta - Tbr1 (assay MGI:7834522).
Structure Cell Type Level Pattern Image Note
TS23: hippocampus radial glial cell Present Regionally restricted S3C' , S3C Reduced expression in the ventricular layer.
Specimen S3D: embryonic day 15.5; Wdr62em2Dng/Wdr62em2Dng (more )
Note: Triple labeled: red - Pax6; green - Eomes (assay MGI:7834523); magenta - Tbr1 (assay MGI:7834522).
Structure Cell Type Level Pattern Image Note
TS23: hippocampus radial glial cell Present Regionally restricted S3D , S3D' Reduced expression in the ventricular layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory